Potpourri
GI
Random Numbers
Cardiology
Radiology
Keep it Local!
100
A newborn male has prolonged bleeding after a circumcision. Laboratory evaluation shows
Hgb 12, platelets 225, PT 15, INR 0.98, PTT 98
These are the most likely diagnoses and biologic causes.
What is hemophilia A (Factor VIII deficiency) and hemophilia B (Factor IX deficiency)?
100
These are the two most common areas that a preterm newborn would have pneumatosis.
What are the terminal ileum and the ascending colon?
100
A 35 week infant has RDS with pulmonary hypertension.
HFOV settings:
MAP 17 amplitude 36 hertz 10 FiO2 0.9 iNO 20ppm
ABG: 7.39/38/56/23
Calculate his Oxygenation Index.
OI=(MAP xx FiO2 xx 100)/(Pa02)
What is 27.3?
100
This percentage of cardiac output goes to the lungs in the fetus.
What is 15-20%?
(increases with advancing gestational age)
100
Describe the radiographic findings.
What is Pneumopericardium?
100
This national landmark (under construction in the photo) was completed in 1965.
This many workers died during
the construction process.
What is zero?
13 deaths
were “budgeted” into the cost
The netting was found to be too narrow to catch anyone falling from the top.
200
Areas of the brain that are most commonly injured in hypoxic ischemic encephalopathy.
What are the basal ganglia, thalamus, and deep nuclear grey areas?
200
This leads to inflammation of jejunal mucosa, blood in stool and eosinophilia in response to formula intake.
What is Non-IgE mediated Cow’s Milk Protein Intolerance?
200
A study has a 90% likelihood of not rejecting the null hypothesis when it's actually false.
Name this type of error.
What is Type II error?
200
The rhythm strip from infant born to mother with SLE
is due to this diagnosis, this pathologic process, and has this long-term prognosis.
What is prolonged PR interval, type I heart block (can range 1st-3rd degree, in utero presentation typically 2nd-3rd)?
What are Anti-Rho/SSA, anti-La/SSB antibodies?
What are irreversible changes to conducting system?
200
Describe the brain findings on the image.
Name the most common genetic cause of this condition.
What is Lissencephaly?
What is the LIS1 gene?
200
The building that houses the 
was once part of an St. Louis leading industry that made this product.
What are shoes?
300
A 4.2 kg IDM infant has a Hct of 72% and blood is noted in his urine.
Name the diagnosis and the 2 other findings associated with this diagnosis.
What is renal vein thrombosis?
What is flank mass and thrombocytopenia?
300
This enzyme is elevated on newborn screens for those with pancreatic duct plugging.
Name the enzyme and the diagnosis.
What is immunoreactive trypsinogen?
What is cystic fibrosis?
300
An 6 week old infant with a large VSD has slow onset tachypneic at rest.
Cardiac cath shows:
pulmonary venous saturation 100%
pulmonary arterial saturation 88 %
SpO2 94%
SvO2 54%
This is his Qp/Qs ratio:
Q_P / Q_S = (S_pO_2 - S_vO_2)/(P_vO_2 - P_aO_2)
= (94-54)/(100-88)
= 2.5:1
300
These fetal cardiac conditions are most commonly associated with hydrops.
What are:
Ebstein's anomaly
Tetralogy of Fallot with Absent Pulmonary Valve
SVT
Fetal heart block
300
An infant with this syndrome has episodic hyperpnea, abnormal eye movements and hypotonia and this brain MRI finding.
What is Joubert Syndrome?
Caused by >35 genes
300
Name this famous celeb and where he grew up in STL.
Who is Yogi Berra?
What is The Hill?
Played in MLB for 19 years, then manager and coach, mostly for Yankees
Famous quote: 'When you come to a fork in the road, take it.'
400
Omphalocele and gastroschisis are abnormalities in the development of this specific part of the body.
What is the midgut?
400
The length of a 24-26 week infant's small intestine.
What is 70cm?
400
A 500 gram infant 23 week infant has a sodium of 150 on DOL 2. This is his free water deficit.
= (Na_(current)-Na_(goal))/(Na_(goal)) xx TBW
= (Na_(current)-Na_(goal))/(Na_(goal)) xx 0.90 xx 0.5kg
= 0.032 L = 32 mL = 64 mL//kg
400
Describe this EKG finding.
What is Atrial flutter with 2:1 conduction?
400
An infant with this syndrome presents with respiratory failure, hypotonia, seizures and radiograph below.
Name the finding and diagnosis.
What is epiphyseal stippling?
What is Zellwegger Syndrome?
Peroxisomal disorder
AR, PEX6 gene
400
Name this local celebrity and her most famous work.
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Who is Maya Angelou?
What are:
I Know Why the Caged Bird Sings (book)
Still I Rise (poem)
"Do the best you can until you know better. Then when you know better, do better. "
500
A 2 day old 24-week infant is receiving TPN through a UVC and 160 Na acetate through the UAC. The infant has narrow pulse pressure, tachycardia, weak pulses, poor cap refill and muffled heart sounds.
Name the diagnosis and the catheter most responsible.
What is a pericardial effusion with tamponade physiology?
What is the UVC?
500
These 2 maternal conditions lead to infants with small left colon syndrome.
What are diabetes and hypothyroidism?
500
Specificity is a property of a test determined by this ratio.
"Specificity" = "True negatives" / ("True Negatives" + "False Positives")
500
The PDA remains patent in utero via this mechanism.
The PDA closes ex utero via this mechanism.
Please be specific.
What are the actions of Prostaglandins (PGE2) and Prostacyclin (PGI2) made by placenta and DA?
What is the effect of Cyclo-oxygenase regulation of PGE2 production?
*Postnatally-administered PGE is PGE1
Closure: Muscle contraction of DNA- sensitive to oxygen (mitochondria>H2O2>depolarization>calcium influx>smooth muscle cell constriction), acetylcholine (COX1 activation), bradykinin (decreases sensitivity to PGE2) and endothelin (vasoconstriction)
500
An abdominal mass in a term infant is evaluated with MRI and shows this diagnosis.
What is Fetus in fetu?
500
St. Louis has many local stars. Name 4 in this tourist commercial.
Jenna Fischer
John Goodman
Sterling K. Brown
Ozzie Smith
Jenifer Lewis
Becky Sauerbrunn
Andy Cohen