Dosage Forms
Liquid dosage form. Need auxiliary label "Shake Well".
Suspension
Mixing/Blending powders by rotating a container.
Tumbling
Plate made of glass used to mix ingredients through spatulation.
Ointment Slab (or Compounding Slab)
Prescription calls for 700 ml of dextrose 8% from D5W and D20W. How much of the D5W will you use?
560 ml
According to the USP <795> the date after which a compounded product should not be used is known as the _________.
Beyond Use Date (BUD)
Used for buccal administration. Made with active ingredients in powder form added into a liquid base that is then solidified.
Troche (or Lozenge)
Rubbing/Grinding/Pulverizing a substance to create a finer particle.
Trituration
Used to transfer solid dosage forms from weighing pans, preparing ointments/creams, transferring to a container, or similar tasks.
Spatula
You need to prepare 100 ml of HCTZ 10 mg/ml. How many tablets of hydrochlorothiazide 25 mg/tab will you need?
40 tablets
A refrigerated aqueous solution or suspension always has a beyond-use-date of ___.
14 days or less
Water-in-oil emulsion that is usually greasy & not water washable.
Ointment
Reducing particle size of a solid during ointment preparation by turning into a paste using an addition agent that stays in the final product.
Levigation
Used for grinding & mixing ingredients. Usually made of glass or porcelain.
Mortar & Pestle
500ml of a 20% potassium chloride solution is ordered by the physician. The stock solutions available are 40% and 10%. How much of each is needed to make this solution? Round to the nearest whole mL.
167 ml of 40% and 333 ml of 10% solution
USP Chapter for non-sterile compounding
USP 795
Oil-in-water emulsion that is non-greasy & water washable.
Cream
A method of combining ingredients of differing strengths into an ointment or cream base.
Geometric dilution
In a graduated cylinder, liquid is measured at the _____.
The bottom of the meniscus
Prepare 60 grams of zinc oxide 20%. How many grams of zinc are contained in this compound?
12 g
A water-based topical cream is compounded on 11/10/24. None of the ingredients expire within the next 6 months. When is the BUD?
12/10/24
Liquid dosage form with solute and solvent.
Solution
Reduces the particle size of a substance by adding an additional ingredient that evaporates later, so it's not part of the final product (e.g. alcohol into a hard, crystalline powder)
Pulverization by intervention
Used for measuring ingredients with counter-weights placed on the right side.
Class III prescription balance
How many grams of sodium chloride are in 3 L of NS?
27 g
What is contained in an SDS?
Information on how to store hazardous substances, and procedures for treatment of accidental spills, ingestion or exposure