Gen Psycho-
pharm
pharm
Primary Care Psycho-pharm
All thing PCMH
100
The main mechanism of action of olanzapine, quetiapine, risperidone.
D2 Blockade
100
What is the methylphenidate IR equivalent of Metadate 40 mg
20 mg BID
100
Can Attention Deficit hyperactivity Disorder be diagnosed in a child with autism spectrum disorder
Yes, but only since DSM5. Prior to that ASD was an exclusion criterion for ADHD
200
The main mechanism of action for aripiprazole, brexipiprazole
D2 partial agonism
200
what is the methylphenidate IR equivalent of amphetamine XR 20 mg
20 mg BID
200
What are common liquid options for youth with ADHD
MTH HCL and MTH HCL ER liquid.
300
Metabolic syndrome (weight gain, dyslipidemia, type 2 diabetes, and high blood pressure) is a known sequela of antipsychotics. What causes this?
Carli M, Kolachalam S, Longoni B, Pintaudi A, Baldini M, Aringhieri S, Fasciani I, Annibale P, Maggio R, Scarselli M. Atypical Antipsychotics and Metabolic Syndrome: From Molecular Mechanisms to Clinical Differences. Pharmaceuticals (Basel). 2021 Mar 8;14(3):238. doi: 10.3390/ph14030238. PMID: 33800403; PMCID: PMC8001502.
300
How long would you expect the clinical effects methylphenidate OROS to last
10-14 hrs
300
What are two Common liquid SSRIS?
Fluoxetine and Escitalopram
400
How does dosing strategy for SSRIS for anxiety differ from SSRI for depression (starting dose, rate of increase, target dose)
Starts the same, increase at the same rate, go to higher doses
400
Complete this sentence:
Methlyphenidate OROS 18,27,54 compares to total daily doses of methylphenidate IR.
Extra credit: how would those be dosed
Methylphenidate IR 15, 30, 45
Extra credit: 5 mg TID, 10 TID, 15 TID
400
Are tics a contraindication to stimulants
No. Risk benefit discussion.
"To date, research has not established a “definitive and causal” relationship of the emergence of tics with stimulant use. Though some studies have indicated that transient tics may occur more often in a population of ADHD patients (with and without a history of tic disorders) treated with stimulants, this data remains controversial. "
Pidsosny IC, Virani A. Pediatric psychopharmacology update: psychostimulants and tics - past, present and future. J Can Acad Child Adolesc Psychiatry. 2006 May;15(2):84-6. PMID: 18392198; PMCID: PMC2277289.
500
5 Physiologic actions of benzodiazepines
1) Anticonvulstant
2) Muscle relaxant
3) hypnotic / amnestic
4) Anxiolytic
5) Sedative
AKA not a good option for maintenance treatment of anxiety in children
500
Two medications FDA approved for GAD for children and adolescents.
Escitalopram and duloxetine.
500
What is the starting dose of fluoxetine for a 8 year old with depression (who is in therapy already).
5 mg is what I would do. 10 is what is in the package insert. Definitely would start at 10 mg for a teen.