The stimulus, food, causes a dopamine surge and acts through glutamatergic neurons in hypothalamus causing neuroplastic changes of food craving.
What is compulsive consumption?
100
This hormone is blunted in binge/purging BN, resulting in diminished dopamine activity and alterations in reward and seeking behavior
What is insulin?
100
This adipokine inhibits NPY/AGRP and stimulated POMC/CART, resulting in decreased appetite and increase TEE
What is leptin?
100
In this health condition, you would observe high levels of androgens associated with reproductive issues and may also observe alterations in ghrelin, CCK, and PYY.
What is PCOS?
200
RMR, TEF, and PA
What are the components of TEE?
200
This is characterized by disruption of reward circuit, alterations in prefrontal cortex resulting in delay discounting or hyperbolic discounting, and dopamine dysregulation.
What is self-control?
200
In BN, basal levels of this hormone are elevated while postmeal levels are decreased.
What is ghrelin?
200
These anorexigenic neurotransmitters act through the PVN to cause increase in TEE
What are POMC/CART?
200
Bone health is altered in this condition. Specifically, altered bone architecture related to leptin resistance and possibly changes in ghrelin and PYY .
What is obesity?
300
purging, cyclic dieting, binge eating, and rumination
What is disordered eating?
300
Craving stimulus leads to alteration in prefrontal cortex and OFC damage, resulting in hyperphagia
What is motivation?
300
This neurotransmitter is downregulated along with its receptor, which is the opposite you would see in cocaine or alcohol dependence, this may be related to response to binging.
What is beta-endorphin?
300
This gut hormone stimulated NPY/AGRP and inhibits POMC affecting appetite and blood glucose.
What is ghrelin?
300
This proinflammatory cytokine is elevated in both obesity and AN and alters insulin sensitivity.
What is TNFalpha?
400
Clinical eating disorder that has some components of AN, BN and BED but not all
What is EDNOS?
400
The awareness of satiety is dysregulated. The specific region of the brain is the insula.
What is craving?
400
Hypersensitivity of the reward circuit center and less craving activation
What are two differences observed in EDs compared to normal?
400
This adipokine stimulates increased glucose uptake, lactate production, and fat oxidation while inhibiting gluconeogenesis.
What is adiponectin?
400
Bone health in this condition is affected by the following alterations: low levels of estradiol, leptin, IGF-1; high levels of cortisol and PYY; and GH resistance.
What is AN?
500
Disordered eating, Bone Health, and Menstrual Status are all components of this - with the recognition that each component has a spectrum of severity.
What is female athlete triad?
500
Alterations in habenula resulting in increased food intake in response to increased stress reactivity, negative mood and discomfort.
What is antireward?
500
This neurotransmitter affects mood state and in EDs increased receptor binding has been reported.
What is serotonin?
500
Both of these gut hormones alter food intake and nutrition absorption. The second of the hormones (answer must be in order) also stimulates fat oxidation and TEE.
What is CCK and PYY?
500
In this condition of menstrual dysregulation, low energy availability is thought to be the driver that disrupts GNRH pulsatility resulting in low LH and ultimately low estradiol and progesterone.