Nucleic Acid Structure
If adenine is 15%, thymine is...
15%
Replication begins at this location in the DNA.
Origin of replication
Unlike bacteria, eukaryotes have multiple of these sites.
origins of replication
New nucleotides on the daughter strand are assembled in this direction.
5' to 3'
This polymerase in bacteria is required to remove and replace the RNA primers.
DNA polymerase I
RNA has this nitrogen base that DNA does not have.
Uracil
These proteins recognize consensus sequences in the DnaA boxes.
DnaA proteins
Unlike bacteria, the chromosomes of eukaryotes are this shape.
Linear
Replication on the leading strand is continuous, whereas replication on the lagging strand is...
Discontinuous
Flap endonuclease performs this function in eukaryotes.
remove the RNA primer only
The part of the double helix where proteins will bind.
Major groove
Once the DNA helix is unwound, replication will proceed in this direction.
5' to 3'
The ORC is required for this step of eukaryotic replication.
initiation
DNA replication on the leading strand is accomplished by this DNA polymerase in eukaryotes.
This protein must recognize the ter sequence to stop the movement of the replication fork.
Tus (termination utilization substance)
This scientist used X-Ray diffraction to analyze the structure of DNA.
Rosalind Franklin
This enzyme is the first to function in the initiation complex.
Helicase
This enzyme, in conjunction with primase, begins the initial replication.
When mismatched base pairs occur on the daughter strand, this enzyme can repair them.
3' to 5' exonuclease
This enzyme is needed to separate the two circular DNA chromosomes in bacteria.
DNA gyrase
This alternative form of DNA may have implications in transcription in yeast.
Z-DNA
Initial separation of the double helix occurs in this region of the initiation complex of DNA.
AT-rich region
If MCM helicase is nonfunctional, this will be the consequence.
The DNA cannot unwind, and replication will not occur.
This subunit operates as a clamp to prevent DNA pol III from falling off the template strand.
beta subunit
A mutation in the telomerase enzyme, preventing its function, would have this consequence.
Chromosomes would get shorter with each round of replication.