Nucleophiles and Leaving Groups v Basicity
Good Bases are ____
What are Good Nucleophiles?
Replacing one atom with another. (ex/ Radical Halogenation)
What is Substitution?
Bromide v Iodide
Which is the better leaving group?
What is Iodide?
The tendency of an atom participating in a covalent bond to attract the bonding electrons. (F>O>N)
What is Electronegativity?
Does this increase or decrease Nucleophilicity?
The year that the College of the Holy Cross was founded.
When is 1843?
Poor Bases make ___ Nucleophiles.
What are Poor Nucleophiles?
"Electron Loving" a substrate that accepts the electrons from the nucleophile.
What is an Electrophile?
Tosylate v Chloride
Which is the better leaving group?
What is Tosylate?
The ability of a system to move its pi electrons within the system.
What is Resonance?
Does this increase or decrease Nucleophilicity?
True or False: There used to be pubs in the common room of all of the Upper Easy Dorms.
True!
Professor Linton's first name.
Who is Brian Linton?
A reaction where a nucleophile replaces a leaving group.
What is Nucleophilic Substitution?
Acetate v Triflate
Which is the better leaving group?
What is Triflate?
A local change in the electron density due to electron-withdrawing or electron-donating groups elsewhere.
What are Inductive Effects?
Does this increase or decrease Nucleophilicity?
What is Malady?
Good Bases make ____ Leaving Groups.
What are "Poor" Leaving Groups?
"Nucleus Loving" an electron-rich species that attacks a carbon nucleus.
Mesylate v Nosylate
Which is the better leaving group?
What is Nosylate?
The ability for an anion to react quickly.
What is a reactive anion?
Does this increase or decrease Nucleophilicity?
True or False: Holy Cross was asked to become a part of the Ivy League.
True!
Poor Bases make _____ Leaving Groups.
What are "Good" Leaving Groups?
The functional group that leaves the carbon atom, taking electrons with it.
What is a Leaving Group?
Who is The Kid Laroi?
The size or 'bulkiness' of a nucleophile. (Consider CN, I, SH)
What is the ease of a backside attack?
Does this increase or decrease Nucleophilicity?
The residence hall that Dr. Fauci lived in his freshman year.
What is Wheeler Hall?