Bergonie and Tribondeau
Lymphocytes, spermatogonia, erythroblasts
What are cells that are highly radiosensitive?
Where in the cell is DNA found
What is the nucleus?
Apoptosis
What is the natural aging process of cells?
Are sebaceous and sweat glands radiosensitive?
No, they are relatively radioresistent.
What is the result of ionizing radiation and a DNA molecule?
Direct effect/ possible genetic mutation
The part of the cell cycle that is considered the most radiosensitive.
What is mitosis (mitotic phase)?
What causes division delay within a cell?
What is "low doses of radiation"?
What is the range of radiation exposure where mitotic division delay may occur but will return to normal?
The dose is usually between 50-300 rad.
What is the breakdown of water using radiation?
Radiolysis
What does LET stand for?
Linear energy transfer.
Undifferentiated, precursor or stem cells.
What are cells that are more radiosensitive than mature cells?
What is considered more radiosensitive- RNA or DNA?
DNA is more radiosensitive
Will you expect a higher cell death rate under oxic(with oxygen) or anoxic(without oxygen) conditions?
Oxic
What is the average lifespan of erythrocytes?
120 days
What is "redness and swelling at site of exposure"?
Inflammation
The metaphase portion of the cell cycle.
What is the phase of the cell cycle when the most chromosome radiation damage can occur?
What is the end result of Meiosis?
4 daughter cells with 23 chromosomes each
What does OER stand for?
Oxygen enhancement ratio
How does a tissue or organ "heal"?
Cellular Regeneration or Cellular Repair
Which of the following is the most radioresistant: Erythrocyte, gastric mucosa, or neuron?
neuron
The nucleus compared to the cytoplasm of the cell.
The nucleus is more radiosensitive to direct effects of radiation when compared to the cytoplasm.
What is the order of the stages of mitosis?
Prophase, Metaphase, Anaphase, Telophase
When discussing OER and LET, one could say____?
OER for low LET radiation is more pronounced than for high LET radiation.
What are the 4 stages of Acute Radiation Syndrome (they might occur within minutes or days/weeks)?
Prodromal, Latent, Manifest, Recovery/Death
What does DNA stand for?
Deoxyribonucleic acid