Hematopoietic Growth Factors
What is the primary function of hematopoietic growth factors?
They stimulate the production of blood cells in the bone marrow.
What is the primary function of colony-stimulating factors (CSFs)?
They stimulate the production of white blood cells in the bone marrow.
What condition is erythropoietin commonly prescribed for?
Anemia, especially in chronic kidney disease patients.
Name a common side effect of hematopoietic growth factors.
Bone pain, fever, injection site reactions, fatigue, headache, nausea, muscle aches.
Name two types of colony-stimulating factors and their specific targets.
1. Granulocyte colony-stimulating factor (G-CSF) targets neutrophils
2. Granulocyte-macrophage colony-stimulating factor (GM-CSF) targets neutrophils, eosinophils, basophils, and macrophages
3. Macrophage Colony-Stimulating Factor (M-CSF) targets monocytes/macrophages
How does erythropoietin work in the body?
It stimulates the production of red blood cells.
How do hematopoietic growth factors benefit cancer patients?
They help replenish blood cells depleted by chemotherapy.
What are common clinical uses of colony-stimulating factors?
They are used to reduce the risk of infection in patients undergoing chemotherapy, to treat neutropenia, and to support bone marrow recovery after transplantation.
What are common side effects of erythropoietin?
Hypertension, headache, flu-like symptoms, injection site reactions, nausea and vomiting, fever, dizziness.
What is the role of granulocyte colony-stimulating factor (G-CSF)?
It stimulates the production of neutrophils.
What are common side effects of colony-stimulating factors?
Bone pain, fever, injection site reactions, fatigue, headache, nausea, muscle aches, allergic reactions, capillary leak syndrome.
What should a nurse assess before administering erythropoietin?
Hemoglobin levels and blood pressure.
What nursing assessment is crucial before administering hematopoietic growth factors?
Checking the patient’s complete blood count (CBC).
What nursing assessments are important before administering colony-stimulating factors?
Assess the patient’s white blood cell count, check for signs of infection, and review the patient’s medical history for any contraindications.
What patient education is important for erythropoietin therapy?
Educate about the importance of regular blood tests and monitoring blood pressure.