Immunity Basics
SLE & JIA
Allergy & HIV
Blood Disorders
Pediatric Cancers
100
This normal trough in infancy occurs between loss of maternal IgG and the rise of the infant's own antibody production.
What is physiologic hypogammaglobulinemia?
100
This hallmark rash of SLE spreads across the cheeks and nose.
What is the malar (butterfly) rash?
100
Allergy is an exaggerated immune response mediated by this immunoglobulin.
What is IgE?
100
Excess consumption of this beverage is a classic cause of iron-deficiency anemia in toddlers.
What is cow's milk?
100
The most common cancer in pediatrics.
What is acute lymphoblastic (lymphocytic) leukemia (ALL)?
200
Proportionally large lymph nodes, tonsils, and thymus in a child are considered this type of finding.
What is an expected (normal) finding, not pathology?
200
The key mechanism behind multi-organ damage in SLE: autoantibody-driven inflammation of blood vessels.
What is vasculitis?
200
Nasal, palatal, or throat itching plus difficulty breathing should make the nurse suspect this emergency.
What is anaphylaxis?
200
Treatment used to remove lead in lead poisoning or excess iron in thalassemia major.
What is chelation therapy (e.g., deferoxamine)?
200
The white 'cat's eye reflex' of the pupil is the classic sign of this congenital cancer.
What is retinoblastoma?
300
This congenital disorder involves absent or nonfunctional T- and B-cell immunity.
What is severe combined immunodeficiency (SCID)?
300
The most common chronic rheumatic disease of childhood.
What is juvenile idiopathic arthritis (JIA)?
300
Beyond EpiPen training, the nurse teaches a child with severe allergy to always wear this.
What is a medical ID alert bracelet/necklace?
300
Crisis triggers for this autosomal recessive disease include infection, dehydration, cold, exertion, and hypoxia.
What is sickle cell disease?
300
For this kidney tumor, the nurse's #1 rule is: DON'T palpate the abdomen.
What is Wilms tumor?
400
This X-linked primary immunodeficiency presents with the triad of thrombocytopenia, eczema, and recurrent infection.
What is Wiskott–Aldrich syndrome?
400
Classic JIA symptom that lasts >30 minutes after rest and improves with movement; nurses ease it with warm morning baths.
What is morning stiffness (gelling)?
400
Given postnatally to the newborn of an HIV-positive mother to prevent transmission.
What is zidovudine?
400
Oral medication used in sickle cell disease to reduce the frequency of crises.
What is hydroxyurea?
400
'PUP is UP': potassium, uric acid, and phosphorus rise in this chemotherapy complication.
What is tumor lysis syndrome?
500
The only curative treatment for severe primary immunodeficiencies such as SCID.
What is bone marrow / stem cell transplant?
500
Because it is asymptomatic early, this JIA complication requires routine eye exams.
What is uveitis?
500
Diagnostic test used to detect HIV in infants younger than 18 months, since maternal antibodies interfere with antibody testing.
What is HIV DNA/RNA PCR?
500
Often following a viral illness, antiplatelet antibodies destroy platelets in this disorder treated with corticosteroids and IVIG.
What is ITP (immune thrombocytopenia)?
500
This distinctive cell identifies Hodgkin lymphoma on biopsy.
What is the Reed-Sternberg cell?
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