Genomics
This condition is the result of a phenylalanine hydroxylase gene mutation such that phenylalanine cannot be metabolized to tyrosine. This leads to the accumulation of phenylketones, which can cause developmental delays, failure to thrive, and neurological symptoms. People with this condition must restrict high protein foods, like meat, eggs, and beans, as well as aspartame.
What is phenylketonuria?
Carcinogenic compounds that form when meats are cooked and charred at high temperatures due to the reaction between amino acids and creatine in muscle protein.
What are heterocyclic amines?
Hormones that stimulate heart rate and blood pressure and increase metabolic rate through promotion of glucagon secretion, glycogenolysis, gluconeogenesis, and fatty acid oxidation.
What are catecholamines?
The cytochrome system by which grapefruit irreversible inhibits the oxidation of drugs like calcium-channel blockers, simvastatin, Xanax, Valium, and Synthroid, increasing drug concentrations in systemic circulation.
What is cytochrome p450?
What the acronym MeSH stands for
What are Medical Subject Headings?
With translocations, amplifications, or point mutations, proto-oncogenes can turn into these overexpressed genes that positively regulate the cell cycle.
What are oncogenes?
Carcinogenic compound that forms in foods during a chemical reaction between asparagine and reducing sugars. Occurs at elevated temperatures when frying, roasting, and baking plant-based foods, such as potato products and grains.
What is acrylamide?
Proteins released by pro-inflammatory cytokines as an acute, systemic response to inflammation. Among these are fibrinogen, serum amyloid A, C-reactive protein, C3, and haptoglobin.
What are positive acute phase proteins?
Low serum concentrations of this negative acute phase protein result in potential for toxicity in patients taking protein-bound medications like Warfarin and Dilantin.
What is albumin?
What the P stands for in PICO
What is population?
Two genetically identical individuals can have vastly different phenotypes primarily due to this epigenetic change that controls a gene's "on/off switch".
What is methylation?
Anti-cancer compound in soy that inhibits angiogenesis and enzymes involved in cell proliferation.
What is genistein?
Percentage of body surface area affected by a burn covering the face, anterior torso, and anterior left arm.
What is 18%?
Serum concentrations of this drug will likely decrease below its narrow therapeutic window with a high fiber diet, delayed gastric emptying, or a sudden introduction of many cruciferous vegetables.
What is Digoxin?
Procedure associated with impaired absorption of divalent cations, vitamin B12 deficiency, and Dumping Syndrome.
What is Billroth II?
A sequence variation in the genetic code. For example, an adenine being converted to a thymine in a DNA sequence.
What is a single nucleotide polymorphism?
Cell cycle specific chemotherapeutic category that prevents the synthesis of DNA building blocks and DNA in the G1 and S phases of the cell cycle.
What are antimetabolites?
Hormone that stimulates the kidneys to reabsorb sodium to ultimately maintain blood volume.
What is aldosterone?
This drug changes the binding site for vitamin K, influencing blood clotting.
What is Warfarin?
Synthetic estrogen that increases cancer risk in the woman who receives it, as well as in her offspring and her offspring's offspring.
What is diethylstilbestrol?
Wilson's disease occurs due to a defective ATP7B transport protein in hepatocytes, a P type ATPase that binds copper to apoceruloplasmin. Copper accumulation in the brain and other tissues leads to oxidative stress. Treatment can consist of this divalent cation bound to tetraionobdylate because this mineral impairs copper absorption.
What is zinc?
Cell cycle nonspecific category of chemotherapeutics that bind to nucleic acids and prevent RNA synthesis.
What are antitumor antibiotics?
The number of calories that a patient would receive in three days from 100 mL Propofol per day.
What is 330 calories?
Divalent cations like iron, zinc, and calcium, chelate this drug.
What is tetracycline?
Daily protein needs of a patient with severe burns who weighs 198 lbs. (90 kg).
What is 180 g?