Neurotransmitters
This neurotransmitter is inhibitory and plays a role in calming the CNS.
What is GABA?
Carbidopa is added to levodopa to reduce this side effect.
What is nausea/vomiting?
This drug enhances cognition by blocking glutamate activity.
What is memantine?
This OTC drug can cause QT prolongation.
What is dextromethorphan?
Priority assessment before starting antiepileptics:
What is reviewing current medications?
This drug improves walking in MS patients.
What is dalfampridine?
This imbalance causes Parkinson’s disease motor symptoms.
What is too little dopamine and too much acetylcholine?
This is the MOST common long-term adverse effect of carbidopa/levodopa.
What is dyskinesia?
This drug is commonly given with memantine to enhance effectiveness.
What is rivastigmine?
Combining donepezil with dextromethorphan can lead to:
What is torsades de pointes?
This route of phenytoin should be avoided due to tissue damage.
What is intramuscular (IM)?
MS drugs increase risk for this complication.
What is infection?
Dopamine agonists improve Parkinson’s symptoms by doing this.
What is increasing dopamine to restore balance?
Dopamine drugs should NOT be taken with this nutrient.
What is protein?
Best location for rivastigmine patches in confused patients:
What is upper or lower back?
Patients on MAO-B inhibitors must avoid this food component.
What is tyramine?
Oxcarbazepine can cause this dangerous electrolyte imbalance.
What is hyponatremia?
Topiramate can cause this metabolic disturbance.
What is metabolic acidosis?
COMT inhibitors improve Parkinson’s therapy by:
What is preventing dopamine breakdown → prolonging effect?
Best timing for dopamine agonists is:
What is 30–60 minutes before meals?
A patient prescribed memantine XR 14 mg only has 7 mg capsules. What should the nurse do?
What is give two 7 mg capsules?
Consuming tyramine while on MAO inhibitors leads to:
What is hypertensive crisis?
Lamotrigine must be stopped immediately if this occurs.
What is rash?
Symptoms of metabolic acidosis include:
What is muscle weakness, hypotension, slow HR?
A patient on levodopa suddenly has worsening tremors before the next dose. What is happening?
What is “wearing-off” effect of dopamine therapy?
A patient on dopamine agonists and antihypertensives becomes dizzy and nearly faints. Why?
What is severe hypotension from additive effects?
Why is combining memantine with cholinergic drugs beneficial?
What is they work by different mechanisms → increased effectiveness?
A patient on MAO inhibitors presents with severe headache and hypertension. Cause?
What is tyramine interaction?
A patient on lamotrigine develops a rash. Priority action?
What is stop the drug immediately and notify provider?
A patient on topiramate has lethargy, vomiting, and confusion. What is suspected?
What is encephalopathy?