Bone Physiology & Risk
Peak bone mass is reached during this age range.
What is 20–30 years old?
This class of drugs slows bone loss in osteoporosis.
What are bisphosphonates?
The most serious adverse effect of bisphosphonates.
What is osteonecrosis of the jaw?
How should oral bisphosphonates be taken?
What is first thing in the morning with plain water?
How should oral bisphosphonates be taken?
What is 1000–1200 mg/day?
A patient lies down right after taking alendronate. What is the risk?
What is esophageal irritation/erosion?
This process breaks down bone and releases calcium into the blood.
What is bone resorption?
This drug is a monoclonal antibody used for osteoporosis.
What is denosumab?
Why should dental procedures be avoided with bisphosphonates?
What is risk for jawbone necrosis?
Why must patients remain upright for 30 minutes after taking bisphosphonates?
What is prevent esophageal damage?
How should calcium supplements be taken for best absorption?
What is with food or shortly after meals?
A patient cannot sit upright after taking a bisphosphonate. Nursing action?
What is hold medication and notify provider?
This life stage accelerates bone loss in women.
What is menopause?
Name one bisphosphonate.
What is alendronate / ibandronate / risedronate / zoledronic acid?
Which symptom may indicate kidney stones from supplements?
What is severe back/flank pain?
Why should bisphosphonates NOT be taken with other medications or food?
What is decreased absorption?
Why should large doses of calcium be divided?
What is prevent GI upset?
A patient on calcium supplements reports constipation and nausea. Interpretation?
What is expected side effects?
Which populations are at highest risk for osteoporosis?
What are Asian and White females?
Which drug class interferes with bone healing and remodeling?
What are bisphosphonates?
Which patients have higher mortality from fractures despite lower diagnosis rates?
What are Black patients?
What is critical to assess before giving oral bisphosphonates?
What is ability to swallow and remain upright?
What is critical to assess before giving oral bisphosphonates?
What is ability to swallow and remain upright?
A patient on osteoporosis meds develops jaw pain after dental work. Priority?
What is suspect osteonecrosis → notify provider immediately?
Explain why bone density declines after age 40.
What is increased resorption > formation?
Why must denosumab be administered by a healthcare professional?
What is risk for serious adverse effects requiring monitoring?
Which medications can contribute to bone loss? (Name one)
What are PPIs, SSRIs/SNRIs, anticonvulsants, tamoxifen, lithium?
What is the MOST important teaching for preventing bisphosphonate complications?
What is proper administration (upright, empty stomach, water only)?
What is the risk of excessive calcium and vitamin D intake?
What is kidney stones?
A postmenopausal woman takes calcium with milk, lies down after alendronate, and reports jaw pain. Identify THREE major concerns.
What are: