I don't feel so good
Which agent is available as a patch for N/V?
Granisetron
Earn 100 points for every one of the 7 cancer warning signs you can name.
Change in bowel/bladder habits
A sore that doesn't heal
Unusual bleeding or discharge
Thickenening of skin or lump
Indigestion or difficulty swallowing
Obvious change in wart or mole
Nagging cough or hoarseness
Which class of medications has a max lifetime cumulative dose due to cardiotoxicity? Name one of the medications in the class.
Anthracyclines - doxorubicin, daunorubicin, idarubicin, epirubicin
Help! Patient has MRSA- what IV options cover MRSA?
100 points for each correct answer
Vanco
Linezolid
Daptomycin
What is used to treat acute diarrhea associated with irinotecan?
Atropine
Patient underwent their first cycle of chemotherapy and had horrible n/v for 2 days after. They are expected to come in for their next cycle next week and they are having severe anxiety at just the thought of coming in. What type of CINV is this and what would you recommend to treat it?
Anticipatory - ativan
What does TNM stand for and what do the letters tell you?
Tumor (T1-T4)
Node (N0-N3)
Mets (M0-M1)
Leucovorin enhances the activity of which agent?
5-FU
What lab abnormalities would you expect with TLS?
hyperkalemia, hyperuricemia, hyperphosphatemia, secondary hypocalcemia
A patient is complaining of having bright red urine, what drug is this associated with?
Doxorubicin
List 3 patient-related risk factors for N/V
Patient’s age (younger than 50), Female, Hx of motion sickness, Hx of n/v during pregnancy, Poor control of n/v in previous chemo cycles, Hx of chronic alcoholism (+ risk factor - decreases incidence of emesis)
What is the purpose of neoadjuvant chemotherapy?
Given to help shrink tumor before resection
Which version of Paclitaxel requires pre-meds and why?
Taxol does due to having cremophor which causes hypersensitivity reactions. Abraxane is bound to albumin and does not have this ingredient
DAILY DOUBLE
In the show the Office, Dwight Schrute is a farmer for what produce?
Which class of medications are notorious for peripheral neuropathy?
Taxanes and vinca alkaloids
List 2 options for breakthrough N/V
Promethazine, proclorpherazine, metoclopramide, dronabinol, Could use zofran if not during the treatment regimen
When considering response to therapy, what does complete response mean?
Complete disappearance of cancer. Does not mean cure
Which agent has the highest incidence of nephrotoxicity and ototoxicity?
Cisplatin
List 3 agents you could use for inpatient IV treatment for febrile neutropenia if there is a concern for pseudomonas.
Penems, cefepime, pip-tazo, ceftazadime
DAILY DOUBLE
What are the four houses in harry potter?
Can an NK-1 receptor antagonist be used to treat N/V?
No it is used for prevention. Not used for breakthrough
What is being measured with a "clinical benefit response"?
Subjective-Pain, QOL, ADLs, breathing improves
The lifetime cumulative dose of Idarubicin is what?
Do not exceed 150 mg/m2
A male patient is undergoing palliative chemotherapy treatment for metastatic pancreatic cancer and his Hgb has dropped to 8. Doctor has written an order for Darbopoetin. Is this appropriate?
Yes, ESAs for anemia are appropriate in patients who are not undergoing treatment for cure.
Mesna is used to help prevent hemorrhagic cystitis for which 2 medications?
Cyclophosphamide and ifosmamide