Numbers & Trends
The Logic of Screening
Lung, Colon, & Cervix
B(r)e(a)st Cancer Essentials
Men & Children
100

This is the second leading cause of death in the United States.

cancer

100

Cancer screening is strictly defined as testing performed only on this group of people.

asymptomatic individuals 

100

Average-risk individuals should now begin colorectal cancer screening at this age.

45

100

This is the most common cause of cancer death specifically for women between the ages of 40 and 50.

breast cancer

100

This is the most common tumor found in men between the ages of 15 and 34.

testicular cancer

200

This term refers to the number of current cases (both new and existing) within a population.

prevalence

200

This pitfall occurs when earlier detection makes it appear that survival has improved, even if the ultimate time of death is not changed.

lead time bias

200

Annual Low Dose CT (LDCT) screening for lung cancer is recommended for adults aged 50–80 who have at least this many pack-years of smoking history.

20 pack-years

200

Women with mutations in these two specific genes have a 60% to 85% lifetime risk of developing breast cancer

BRCA1 and BRCA2

200

The usual cut-off for cancer detection when using the Prostate Specific Antigen (PSA) blood test is this many micrograms per liter.

4 μg/l

300

Successful treatments will increase this specific statistic if the incidence of the disease remains the same.

prevalence

300

This bias involves detecting slow-growing cancers that would not have caused the patient’s death, leading to potential overdiagnosis.

length time bias

300

This virus is the primary risk factor for cervical cancer and can be prevented by a vaccine typically recommended for ages 9–26.

Human Papillomavirus (HPV)

300

The American Cancer Society recommends that high-risk women (such as those with BRCA mutations) receive a mammogram AND this imaging test every year starting at age 30.

breast MRI

300

These two biomarkers are used to monitor patients after they have received treatment for testicular cancer.

Beta HCG and AFP (Alpha-fetoprotein)

400

Among both men and women in the U.S., this is the number one cause of cancer mortality

lung and bronchus cancer

400

This three-letter system is the standard used to stage the extent of a cancer's spread

TNM system (Tumor, Nodes, Metastases)

400

This screening method for colorectal cancer can decrease incidence by over 50% but requires a full colon clean-out and patient sedation.

colonoscopy

400

This life event, especially if it occurs before the age of 30, is considered a protective factor against breast cancer.

pregnancy

400

Also known as Nephroblastoma, this pediatric kidney tumor occurs most often in children between ages 2 and 5.

Wilms Tumor

500

This racial group faces the highest death rate and shortest survival for cancer in America

African Americans

500

Unlike staging, which identifies the "where," this histological process determines how aggressive the cancer cells appear under a microscope.

grading

500

For women aged 21–29, the USPSTF recommends this specific screening test every three years.

Pap cytology

500

A large randomized trial in Shanghai concluded that intensive instruction in this practice did not reduce mortality but did increase the number of benign biopsies

Breast Self-Exam (BSE)

500

This syndrome, which includes aniridia (absence of the iris) and mental retardation, is famously associated with Wilms Tumor.

WAGR syndrome

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