The informal industry group significantly responsible for creating the opioid epidemic.
What is Big Pharma
100
The location of the opioid receptors.
What are the brain, spinal cord, and GI tract.
100
3 most important vital signs a nurse needs to obtain when monitoring a patient who is receiving opioids.
What are pulse oximetry, respiration and heart rate.
100
This new medication in research does not stimulate the dopamine pathways in the brain.
What is PZM21
200
Morphine was used extensively during this war.
What is the Civil War.
200
The condition that actually often occurs when patients with chronic pain are treated with opioids - rather than the pain relief that had been sought.
What is "hyperalgesia"
200
This part of the brain is affected in respiratory depression.
What is the medulla oblongata.
200
3 serious signs and symptoms of opioid overdose.
What are decreased level of consciousness, pinpoint pupils, changes in heart rate, decreased or absent respirations, cyanotic lips and nails, seizure activity, or muscle spasms.
200
This medication in research is made from the leaves from a Southeast Asian tree related to coffee.
What is Kratom (mitragynine pseudoindoxyl)
300
Synthesized in 1806.
What is Morphine.
300
The "gateway" to heroin addiction for 80% of users.
What are prescription painkillers.
300
These receptors are responsible for enabling the body to experience pain.
What are Delta receptors.
300
A serious side effect of opioid overdose.
What is respiratory depression.
300
A new opioid property that targets the known or expected routes of abuse, such as crushing in order to snort or dissolving in order to inject
What is Adverse Deterrent
400
The amount of government spending related to addiction that is actually allocated to prevention and treatment of addiction itself.
What is 2%
400
These are necessary for the supraspinal analgesic effects from narcotics; they are also responsible for the feelings of euphoria associated with opioid use.
What are Mu receptors.
400
This opioid analgesic depresses pain impulse transmission at the spinal cord level by interacting with opioid receptors. It is used in treatment of opioid addiction.
What is methadone (Dolophine).
400
A clinical-stage company developing a topical, non-opioid medicine for localized pain
What is Vapogenix, Inc
500
The rise in the death rate due to opioid overdose between 1999 and 2008.
What is around 400%
500
Opioids work by chemically binding to these specific proteins.
What are opioid receptors.
500
This antidote reverses the adverse effects of the opiates due to its antagonistic actions.