Synthetic Man-Made
Semi-Synthetic
Natural Opioids
History of Opioids
Effects on the Brain
100

What is a synthetic opioid made completely in a lab?

Fentanyl, Methadone, or Carfentanil

100

What does “semi-synthetic” mean?

Made from natural opioids but changed in a lab

100

What plant do natural opioids come from?

The opium poppy

100

Who were the first group of people to discover opium?

Ancient Sumerians

100

What do opiods release in the brain which cause you to feel euphoric?

Dopamine

200

Why are synthetic opioids more dangerous than natural ones?

Extreme potency, rapid action, and a mixture of other drugs

200

Name one semi-synthetic opioid.

Oxycodone, Oxymorphone, or Hydromorphone

200

Name a natural opioid.

Morphine, Codeine, or Thebaine

200

What philosopher later documented opiums medical use for pain relief?

Hippocrates

200

What part of the body is affected when opioids slow breathing?

The Brainstem

300

What synthetic opioid is often illegally mixed into other drugs?

Fentanyl

300

How can semi-synthetic opioids lead to addiction?

They cause tolerance and dependence over time

300

What is the main medical use of natural opioids?

Pain relief

300

Which specific opioid was isolated in the 19th century for its medical purposes?

Morphine 

300

What do opioids do inside your brain and why are they deadly?

Opioids bind to the receptors in the brainstem which can temporarily cancel pain signals but also slow breathing down and cause carbon dioxide buildup

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