Pathophysiology
Osteogenesis imperfecta primarily affects the production of
What is Collagen ?
Which common physical sign is seen in children with OI?
what is a blue sclera ?
What is the primary imaging technique used to detect fractures in a child suspected of having OI?
A. MRI
B. X-ray
C. CT scan
D. Ultrasound
what is XRAY ?
Which is the most important nursing intervention to prevent fractures in a child with OI?
A. Encourage low-impact activities and gentle handling
B. Promote high-impact sports
C. Restrict all physical activity
D. Encourage rough play to strengthen bones
what is A. Encourage low-impact activities and gentle handling
A common musculoskeletal complication of OI is:
A. Scoliosis (curved spine)
B. Asthma
C. Seizures
D. Skin infections
what is A. Scoliosis (curved spine)
OI results in bones that are
What is Brittle and fragile bones ?
Which dental problem is associated with OI?
what is discolored, fragile teeth ?
Which laboratory value is typically normal in children with OI?
A. Serum calcium
B. Alkaline phosphatase
C. Parathyroid hormone
D. Vitamin D
what is A. serum calcium ?
Which intervention helps promote bone strength in children with OI?
A. Encourage a diet rich in calcium and vitamin D
B. Restrict all calcium intake
C. Avoid sunlight exposure
D. Limit fluid intake
what is A. Encourage a diet rich in calcium and vitamin D
Which respiratory complication can occur in severe OI cases?
A. Respiratory failure due to chest deformities
B. Pneumonia from infection only
C. Asthma exacerbations
D. Cystic fibrosis
what is A. Respiratory failure due to chest deformities
Which system of the body is most affected by OI?
Hearing loss in children with OI is often due to
Defects in middle ear bones
Which lab value is generally NOT affected in children with OI?
A. Serum calcium
B. Parathyroid hormone
C. Serum creatinine
D. Alkaline phosphatase
what is C. serum creatinine
For children with severe OI, which treatment may be part of the care plan to strengthen bones?
A. Bisphosphonate therapy (pamidronate)
B. Antibiotics
C. Insulin therapy
D. Steroid therapy
what is A. Bisphosphonate therapy (pamidronate)
Which eye complication is sometimes seen in OI?
A. Vision loss due to retinal detachment
B. Cataracts
C. Glaucoma
D. Color blindness
what is A. Vision loss due to retinal detachment
A lack of functional collagen leads to
What is increased fracture risk ?
Which of the following is NOT a typical manifestation of OI?
A. Repeated fractures
B. Blue sclera
C. Increased bone density
D. Hearing loss
what is C. increased bone density ?
On X-ray, a pediatric patient with OI is likely to show:
A. Multiple fractures at various stages of healing
B. Bone tumors
C. Completely normal bones
D. Joint dislocations only
what is A. Multiple fractures at various stages of healing ?
Which psychosocial intervention is important for children with OI?
A. Encourage participation in safe social and school activities
B. Isolate the child to prevent injury
C. Ignore the child’s feelings about their condition
D. Discourage friendships due to fragility
what is A. Encourage participation in safe social and school activities
Which complication can result from frequent immobilization following fractures in children with OI?
A. Pressure ulcers
B. Increased bone density
C. Enhanced mobility
D. Decreased pain
what is A. Pressure ulcers
In addition to bones, which other tissue is affected due to collagen defects in OI?
A. Sclera, teeth, and ligaments
B. Liver and pancreas
C. Lungs and heart
D. Brain and nerves
what is A. Sclera, teeth, and ligaments
A child with OI may have delayed motor development due to:
A. Pain and fractures limiting movement
B. Cognitive impairment
C. Muscle weakness unrelated to bones
D. Vision problems
what is A. Pain and fractures limiting movement ?
Which prenatal diagnostic method can sometimes detect severe forms of OI?
A. Prenatal ultrasound
B. Amniotic fluid alpha-fetoprotein
C. Maternal serum glucose
D. Fetal echocardiography
what is A. Prenatal ultrasound ?
Which assistive device is appropriate to support mobility in children with OI?
A. Wheelchair or walker for stability
B. Running shoes for jogging
C. No assistive devices needed
D. High heels to improve posture
what is A. Wheelchair or walker for stability
What is a potential complication of bisphosphonate therapy in children with OI?
A. Hypocalcemia
B. Hypercalcemia
C. Increased fracture risk
D. Kidney failure
what is A. Hypocalcemia ?