Lobes of Steel
True or False. Conventional wisdom long held that animal (and human) brains were malleable - that brains could grow/renew themselves.
False.
True or False. Antidepressant treatment can block or reverse the effects of stress and depression.
True
What was the name of the investigator who wrote "Neurotrophic factors and regulation of mood: Role of exercise, diet and metabolism?"
(first or last name fine)
Ronald S. Duman
What is the term for "creation of new neurons?"
A. Neurotropism
B. Neurogenesis
C. Gametogenesis
D. None of the above
B. Neurogenesis
Which of the following is not one of the nerve growth factors mentioned in the reading?
A. Brain Derived Neurotrophic Factor (BDNF)
B. Neurotrophin-3 (NT3)
C. Nerve growth factor (NGF)
D. They are all mentioned in the reading
D. They are all mentioned in the reading
Which structure is one of two neurogenic zones in the adult brain (hint: limbic system)?
Hippocampus
What is the difference between a functional MRI (fMRI) scan vs standard MRI scan?
A. fMRI shows the size of the brain while standard MRI doesn't
B. fMRI shows the shape of the brain while standard MRI doesn't
C. fMRI tracks blood flow and electrical activity while standard MRI doesn't
D. All the above
C. fMRI tracks blood flow and electrical activity while standard MRI doesn't
Which of the following has been found in depressed patients?
A. Decreased BDNF in the hippocampus or prefrontal cortex
B. Increased levels of BDNF in serum samples
C. Elevated levels of neurogenesis
D. None of the above
A. Decreased BDNF in the hippocampus or prefrontal cortex
Name two growth factors whose expressions in the body are increased after antidepressant treatment.
(abbreviations are fine)
BDNF, Fibroblast growth factor 2 (FGF2), Vascular endothelial growth factor (VEGF)
What was (were) the important result(s) of Gage's study with mice and deceased cancer patients?
A. The human brain is not capable of neurogenesis
B. The human brain is indeed capable of neurogenesis
C. Exercise has the potential to promote/enhance the rate at which the brain renews itself (aka neurogenesis)
D. Two of the above are correct
D. Two of the above are correct
Mice with partial to complete deletion of the BDNF gene exhibit which of the following symptoms?
A. Decreased food intake
B. Increased body weight
C. Decreased locomotor activity
D. All of the above
B. Increased body weight
What is the rodent equivalent of an I.Q. test?
(what is the contraption called?)
Morris water maze
What are the two biomolecules mentioned in the reading that may be linked to neurogenesis?
A. Serotonin and dopamine
B. Serotonin and IGF-1
C. IGF-1 and leptin
D. GABA and Serotonin
B. Serotonin and IGF-1
Which of the following results can exercise and dietary restriction induce?
A. A reversal of decreased neurogenesis
B. An increase in antidepressant-like benefits
C. A decrease in neuronal atrophy
D. All of the above
D. All of the above
Who is responsible for the following quote: "We've always known that our brains control our behavior... but not that our behavior could control and change the structure of our brains?"
(first or last name fine)
Fred H. Gage
What is the brain structure whose volume is impacted by things like stress, anxiety/depression, and exercise?
Hippocampus