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100

What is a leading cause of death in the postpartum period?

What is an overdose?

100

How does methadone work?

It binds to the mu receptor?

100

What is the average daily methadone dose?

What is 120 mg?

100

On average, how many dose adjustments are needed for methadone during pregnancy?

What is 3?

100

What test should be obtained before and during treatment with methadone?

What is an EKG?

200

Which forms of oral buprenorphine have the highest bioavailability?

What is buccal and sublingual?

200

What is the ceiling effect with buprenorphine?

What is increasing the dose beyond a certain point does not result in increased effects?

200

How long does it take a buprenorphine tablet/film to dissolve?

What is approximately 30 minutes?

200

Does McLeod have an orderset for buprenorphine induction?

What is yes, it can be found under Opioid Withdrawal Buprenorphine Induction?

200

How is buprenorphine primarily metabolized?

What is through the liver?

300

What kind of labs should be monitored with buprenorphine?

What are liver enzyme tests?

300

What is the max daily dose of buprenorphine?

What is 32 mg?

300

Can Suboxone be used for OUD in pregnancy?

What is yes?

300

What adverse pregnancy outcomes can pregnant women face?

What are preterm labor and neonatal abstinence syndrome?

300

When should MOUD be initiated in pregnancy?

What is as soon as possible?

400

How does buprenorphine work?

What is a partial agonist at the mu-receptor and an antagonist at the kappa-receptor?

400

What is the typical frequency for buprenorphine for OUD?

What is daily?

400

What dose of buprenorphine will most moms be stabilized on?

What is 8 to 16 mg daily?

400

What medication can be added as an adjunct to buprenorphine?

What is clonidine?

400

How long does it take for steady state to be reached for buprenorphine?

What is approximately 1 week?

500

What is the half-life of methadone in pregnancy?

What is 8 hours?

500

If your mother has severe hepatic dysfunction, can they use buprenorphine?

What is no?

500

These patients have a higher tolerance to methadone and require careful titration.

What are patients who used illicit fentanyl?

500

What other disease state should be screened for when using buprenorphine for OUD?

What is hepatitis?

500

Does methadone or buprenorphine have a higher risk of illicit drug use concurrently?

What is buprenorphine?

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