Ovarian Anatomy
The veins that directly drain the Ovary
Ovarian pampiniform plexus
Label the histology slide(Picture 2)
What is Chorion and Amnion
what are at least 3 risk factors Ovarian Fibroma
BRCA1/BRCA2 gene mutations
HNPCC Syndrome
peutz-jeghers Syndrome
Elevated number of lifetime ovulations
infertility/low number of pregnancies
PCOS
Early menarche/late menopause
The hormone that converts androstenedione to Estradiol
What is Aromatase
Most common type of Ovarian tumor
Serous (papillary serous)
The two arteries ligated in an Oophorectomy
What is the Ovarian artery and Ovarian branch from Uterine artery
The fluid analysis from a pleural effusion for ovarian tumors would demonstrate these labs and this type of exudate
High Protein and LDH
Exudative Picture 5
Age of presentation for ovarian Fibroadenoma
what is peak incidence of 60-70
in females this cell is able to produce androstenedione but not estrogen in response to this hormone
What is thecal cells responding to LH
What is the prognosis for Mucinous Ovarian Tumor
What is mostly good prognosis
75% of cases are benign
The route of obtaining Ovarian tissue to evaluate it histologically
What is Oophorectomy
Never do FNA on ovary of testicles it could spread the cancer
What is a pearl sized nodule at the anterior TFL and one at the pubic tubercle
What is the broad ligament and Ovary/urethra/abdomen
Ascites and ABD pain
Cancer Cachexia
disruption in menstrual cycle
pleural effusion->SOB
ABD mass/Pelvic mass
Sox 9 inhibits this hormone in males
what is WNT4(Picture 3)
Prognosis for Serous Cystadenocarcinoma
What is Poor
This is the most aggressive type of ovarian cancer
These three things susspend the Ovary in in the pelvis
Call Exner bodies are a sign of this type of Cancer
Granulosa cell tumors - presents with post menopausal bleeding due to estrogen and progesterone production
The first symptom a patient often present with in ovarian Fibroma?
what is increased abdominal girth/clothes no longer fit
this is why CA-125 is used to monitor Ovarian Cancer
- endometriosis, menstruation, liver disease, PID, Uterine fibroids, pregnancy
Where does malignant cancer come from commonly to the Ovary Name at least 2
GI tract or breast
Endometrial cancer
Malignant lymphoma
Every team answers
Team 1 what is the US findings of a benign ovarian mass
Team 2 what is the US of a malignant ovarian mass
Team 3 give a differential for an ovarian mass/adnexal mass
Picture 4
Due to failure of these two structures patients develop uterine prolapse
What is cardinal ligament and Uterosacral ligaments
These thing will reduce the risk of Ovarian Cancer
What is
Breast feeding, Tubal ligation, GnRH analogs
Tumor markers for ovarian cancers must list 3
What is CA-125
AFP - Yolk Sac tumors
bHCG - non-gestational carcinoma
Inhibin b - Granulosa cell tumor
Female Equivalent to Male Seminoma
what is Dysgerminoma
Occurs in 20-30y/o
Most common type of malignant ovarian tumor for young Women