Burning, electric-shock-like pain with tingling and allodynia is most characteristic of this broad pain mechanism.
What is neuropathic pain?
Antidepressant class commonly used for neuropathic pain.
What is TCAs?
Strengthening, graded activity, gait training, and maintaining mobility fall under this major nonpharmacologic intervention.
What is physical therapy?
A patient with localized post-herpetic neuralgia cannot tolerate systemic medication. This topical anesthetic may be considered.
What is topical lidocaine?
Damage or disease affecting this system is required for pain to be classified as neuropathic.
What is the somatosensory nervous system?
A patient with knee osteoarthritis describes aching pain triggered by walking, without sensory loss or allodynia. This pain mechanism is most likely responsible.
What is nociceptive pain?
Abrupt discontinuation of this type of medication for neuropathic pain may cause flu like symptoms, arthralgias, insomnia, nauseas, anxiety, imbalance.
What is SNRIs (Duloxetine)?
This psychological therapy helps patients modify maladaptive thoughts and behaviors surrounding chronic pain.
What is cognitive behavioral therapy, or CBT?
This topical treatment works through TRPV1 receptor activation and may be used for localized peripheral neuropathic pain
What is capsaicin?
Primary sensory neuron cell bodies carrying pain and temperature from the limbs and trunk are located in this structure.
What is the dorsal root ganglion?
Severe burning pain and marked touch-evoked allodynia remain in a dermatomal distribution months after a vesicular rash resolved.
What is post-herpetic neuralgia?
This type of MOA of anticonvulsants have been shown to decreased trigeminal neuralgia pain?
What are sodium channel blockers (Tegretol, Trileptal, Phenytoin)?
A patient with focal painful diabetic neuropathy has persistent symptoms despite oral therapy. A wearable device that delivers low-voltage electrical stimulation through the skin may be tried as an adjunct.
What is TENS (transcutaneous electrical nerve stimulation)?
A patient with severe breakthrough neuropathic pain needs short-term rescue treatment while long-term therapy is being adjusted. This medication may be considered cautiously for that purpose.
What is Tramadol?
Sensation of pain in the face is relayed in this nucleus of the thalamus?
What is VPM (Ventral posterior medial nucleus)?
A patient develops sharp, shooting pain radiating from the lower back into the posterior leg, accompanied by numbness and a diminished ankle reflex.
What is radiculopahty?
A 78-year-old with painful neuropathy has recurrent falls, constipation, urinary retention, and cognitive impairment. This commonly used first-line drug class would be relatively unattractive because of its anticholinergic and sedating effects.
Name of list of medications that should be avoided in the Elderly?
What is Beers Criteria?
Persistent lumbar radicular pain despite medications and physical therapy may lead to consideration of this procedure, which delivers corticosteroid into the epidural space.
What is an epidural steroid injection?
Increased responsiveness of spinal and supraspinal pain pathways after persistent nociceptive input is known as this process.
What is central sensitization?
A patient reports burning and electric pain over the lateral thigh with numbness but no weakness or reflex changes. The symptoms are caused by entrapment of the lateral femoral cutaneous nerve.
What is meralgia paresthetica?
Gabapentin and pregabalin reduce excitatory neurotransmitter release by binding this auxiliary voltage-gated calcium-channel subunit.
What is the α2δ subunit?
Mnemonic used for acute treatment after neuromuscular injury?
What is RICE?
-Rest
-ICE
-Compression
-Elevation
A patient with severe focal neuropathic pain remains symptomatic despite medications and topical therapy. A targeted injection around the affected nerve may be considered as this type of intervention.
What is peripheral nerve block?
Loss of inhibitory control in the dorsal horn can contribute to amplification of pain through reduced activity of these neurotransmitters.
What are GABA and glycine?