Basics + Physiology
type of structure where loss of one segment can compromise the whole structure
what is a serial organ?
best imaging scan to evaluate the spinal cord before SBRT?
what is magnetic resonance imaging?
amount of healthy liver volume in cubic centimeters that must be spared from high dose radiation
what is 700 cc?
Foundational randomized trial showing that treating limited cancer spots with high dose radiation improves survival
what is the SABR comet trial?
type of immune therapy drugs that are generally safe to give with radiation but not on the exact same day
what are immune checkpoint inhibitors?
maximum number of treatments to be considered sbrt
what is 5?
major bone complication that can happen if high dose is given to weight bearing bones?
what is a compression fracture?
number of treatments that works just as well as 4 treatments for small outer lung tumors per the SAFRON study
what is 1?
type of cancer proven to benefit from treating limited spots in the stomp/oriole and wolverine trials
what is prostate cancer?
type of targeted cancer drugs that increase bleeding risk and must be stopped before treating the trunk
what are VEGF inhibitors?
biological effective dose number needed to achieve ablative local tumor control
what is 100 bed10 ?
primary outcome that was doubled at 3 months in the CCTG 24 trial for spine radiation?
what is complete pain response?
2 types of cancer that commonly spread to the lungs and need higher radiation doses to control given radio resistance?
what are colorectal cancer and sarcoma?***
would also accept RCC
patient performance status where SBRT may cause more harm than good?
What is ECOG 3 or higher?
Commonly utilized blood vessel blocking drug that must be stopped for at least 1 week before and after radiation
what is bevacizumab [avastin]?
tumor movement distance in millimeters that requires active motion management when it is larger than
what is 5?
The number of subdivisions of the spinal bone as delineated in SBRT consensus contouring guidelines
What is 6? [body, pedicle, transverse, spinous, other transverse, other pedicle]
lamina is not its own subdivision
liver disease severity score that assesses risk of liver failure after RT
what is child pugh score? [careful at B or C]
name for when a tumor shrinks outside the radiation field after giving radiation and immunotherapy
what is an abscopal effect?
type of common systemic therapy for prostate cancer that is can be given concurrently with radiation without increasing RT toxicity?
what is ADT?
radiobiological model that tends to overestimate how well radiation works at high doses per treatment
what is the linear quadratic model?
safe lifetime dose limit in eqd2 gray for the spinal cord when giving repeat radiation assuming 1 year between treatments and 50% recovery
What is 45 Gy?***
location term for a lung tumor that touches the main bronchus or major blood vessels
what is ultracentral?
most common type of cancer treated in the dutch belgian liver radiation registry
what is colorectal cancer?
maximum number of weeks you need to pause tki drugs before and after treating the abdomen or liver
what is 2 weeks?