Dankreas
The endocrine portion of the pancreas, composed of 5 different cell types, is arranged in these structures.
What are the Islets of Langerhans?
Name the cell types for a bonus 100.
Are these ducted or ductless?
This vitamin is stored in the body as retinol and is found in egg yolks, milk, liver, cheese, and butter.
What is vitamin A?
Deficiency of this vitamin may cause easy bleeding and bruising with an elevated PT.
What is Vitamin K?
This city, built on more than 100 small islands, is the capital of Indonesia.
What is Jakarta?
This broad term refers to reduced pancreatic enzyme activity, primarily pancreatic lipase, in the intestinal lumen, below the threshold required for digestive functions.
What is Exocrine pancreatic insufficiency?
See steatorrhea, flatulence, weight loss, and abdominal pain of variable location and severity; disease is associated with impairment of quality of life, increased risk of complications due to malnutrition and changes in bone density, and increased motility risk.
What are micelles?
Extremely rare, deficiency of this vitamin is seen in patients with fat malabsorption, abetalipoproteinemia (defect in microsomal transfer protein), and hypobetalipoproteinemia (mutation in apolipoprotein B) disorders, and causes limb/truncal ataxia, hyporeflexia, and upward gaze limitations.
What is vitamin E deficiency?
This legendary coach at the University of Tennessee is the first woman coach to post her 800th win in 2003.
Who is Pat Summit?
The two principal causes of EPI.
What are chronic pancreatitis in adults and cystic fibrosis in children?
REMEMBER TIGER-O
Toxic-Metabolic, Idiopathic, Genetic, Autoimmune, Recurrent, and Severe Acute Pancreatitis, Obstructive
Specifically, acute pancreatitis, pancreatic tumors, diabetes mellitus, celiac disease, inflammatory bowel disease, bariatric surgery, human immunodeficiency virus (HIV)/acquired immunodeficiency disease (AIDS), and genetic and congenital causes
Location of 25-hydroxycholecalciferol's further hydroxylation to its biologically most active form, 1,25-dihydroxycholecalciferol.
What are the kidneys?
This occurs via 1-a-hydroxylase, which is tightly regulated by which hormone (100)?
Pathognomic finding in vitamin A deficiency (hint: 2 words, possessive).
What are Bitot's spots?
This player intercepted Kurt Warner and returned the pick 100 yards for a touchdown in Super Bowl XLIII.
Who is James Harrison?
The gold standard test for diagnosing EPI.
What is the 72-hour fat quantification and determination of fat absorption coefficient?
- Fecal elastase-1 is reliable, <15mcg/g highly sensitive
- breath test measuring fat digestion by pancreatic lipase
- direct secretin-cholecystokinin stimulation test is invasive and time-consuming
This vitamin inhibits the generation of ROS during fat oxidation.
A 2-year-old girl presents with a runny nose, cough, and red eyes for the past 3 days. She is a refugee from Syria and her vaccination status is unclear. Vital signs are temperature 38.5° C (101.3° F), heart rate 100 bpm, and respiratory rate 18 breaths/min. On physical examination, white spots are visible on her buccal mucosa. The doctor prescribes the necessary treatment.
This organ stores the micronutrient used to treat this condition.
What is the liver?
Vitamin A used in the treatment of children with measles.
The name of the largest tree in the world (by volume).
What is General Sherman in California?
almost 3k years old! 275 ft tall, 102.6 ft diameter
This enzyme displaces bile salts to allow pancreatic lipase to hydrolyze triglycerides.
What is colipase?
Cholesterol ester hydrolase and phospholipase A2 hydrolyze cholesterol and phospholipids.
The factors and proteins activated by vitamin K.
What are Factors 10, 9, 7, 2, and proteins C and S?
Describe the mechanism behind pancreatic insufficiency secondary to cystic fibrosis.
Fibrosis, secretory material collecting within the ducts, creating obstructive destruction of acinar tissue, destruction of tissue, blah good job
https://www.sciencedirect.com/science/article/pii/S1569199317308135
85% of CF patients have EPI
What is a flamboyance?