Correct drug/dose/route for a narcotic overdose?
Naloxone - 400mcg IV/IM/IO/IN
Salbutamol is a part of what TWO classifications of medication?
What is a Beta-2 agonist / Bronchodilator
These TWO routes of administration are considered to have the fastest onset of action.
IV/IO
These are the 4 processes of pharmacokinetics.
Absorption, Distribution, Metabolism, Excretion
Which medication as variable effects dependent on the dose and is know for dissociation. Hint* can cause hypotension in catecholamine depleted patients.
What is Ketamine
Your patient has Prolonged QT syndrome. Which is a contraindication for this medication.
Ondansetron
The amount of active drug that reaches systemic circulation in its unchanged form.
Bioavailability
500mcg IM q 5 NO MAX
Adrenaline 1:1000
A classification of medication that often ends in -olol.
Beta blockers
This term, compares the strength of a drug.
Potency
The process of elimination of medications/drugs involves these two processes.
Metabolism and excretion.
Pt has a HR of 44 and signs of circulatory compromise.
Atropine 600mcg IV/IM
This medication is contraindicated when you are using it to treat a traumatic haemorrhage and the bleeding started more then 3 hours prior.
TXA
______ bind to and activate a receptor, producing a similar or the same biological response as the intended chemical.
Agonists
Hydrocortisone
100mg IV/IO/IM
This is the classification of atropine.
Decreases Myocardial workload by reducing myocardial oxygen demand by reducing preload and afterload.
What is Morphine
Plasma proteins in the blood bind to portions of the drug creating ____ _____ ________.
Drug protein complexes
Your pt is experiencing status epilepticus. After initial management of the airway, breathing, and circulation, you consider administering one of these two medications.
Diazepam and Midazolam
Do NOT administer this medication to a patient with the following:
Respiratory depression (adult <10 breaths per minute, child <20 breaths per minute).
Hypotension (actual, not estimated, systolic blood pressure <90 mmHg in adults, <80 mmHg in school children, <70 mmHg in pre-school children).
Morphine
Controls the manufacture and distribution of medicines for human and animal use.
Medicines Act 1968
40 mg IV
Furosemide
Anticholinergic bronchodilator indicated for asthma, reversible bronchoconstriction secondary to Salbutamol administration in patients suffering from bronchospasm. (med/dose/route)
Ipratropium 500mcg nebulised
Your patient is currently in cardiac arrest in PEA. You would NOT consider administering this antiarrhythmic medication that is commonly administered during cardiac arrest.
Amiodarone
These are classified based on their selective action and named according to the transmitter hormones with which they interact.
Receptors
Pt is in cardiac arrest with VT, you are on your 5th shock and have administered adrenaline, you are now considering your second dose of this antiarrhythmic.
Amiodarone 150mg IV/IO
This medication should NOT be given by IV injection because of increased vomiting associated with IV use.
Glucagon
__________is when drug A and drug B given together still only produces their intended effects ,as if they were given individually.
Addition/Summation
Chlorphenamine PO
4mg
Also known as H1 receptor antagonists or H1 receptor blockers, are among the most commonly used medications in the world not only for prevention and treatment of symptoms in allergic rhinitis, allergic conjunctivitis, and urticaria,
Anti-histamines
All types of narcotics are known as a _____________, which allows them to create sedation.
CNS depressant
This is the process of transferring a signal throughout an organism, especially across or through a cell.
Signal transduction
Pt has a BM of 1.8, is unable to follow commands and does not have IV access.
Glucagon 1mg IM
A contraindication for this medication is "Suspected or known systemic infection, tuberculosis, ocular herpes, worm and fungal infections unless specific anti-infective therapy being used."
Prednisolone
_________ bind to a receptor and block or reduce its activation by another substance.
Antagonists
Benzylpenicillin Sodium
1.2g IV/IO/IM
This class of medication is used to manage seizures. (not anti-convulsants)
Benzodiazepines
List 5 major signs and symptoms of opiate overdose
Pinpoint pupils, Hypotension, Bradycardia, Respiratory Depression, Hypothermia (CNS Depression), Coma or death
This is the process of converting drugs to their metabolites
Pt suffering from severe acute asthma not responding to nebulisation treatments (Sal and IB) or steroids.
Magnesium Sulfate 2g IV
Reduced GCS with liver cirrhosis, cardiogenic shock, severe renal failure with anuria, and children under 18 years old. Are contraindications for this medication.
Furosemide
This Act controls the export, import, production, supply and possession of dangerous or otherwise harmful drugs.
Misuse of Drugs Act 1971
Comes in a tube containing 25g
Glucose 40%
Sympathomimetic that stimulates alpha, beta-1, and beta-2 receptor sites
Adrenaline
You administer this medication too quickly and you patient experiences extrapyramidal reactions. (include med/dose/unit/route)
Metoclopramide 10mg IV
This is when a drug is metabolized at a specific location in the body that results in a decreased concentration of active drug when it reaches the site of action or systemic circulation.
First pass effect
First line medication for pt with PPH where Syntometrine is unavailable.
Misoprostol 800mcg SL/PR
If you give this medication to patients with cardiac transplants; their hearts will not respond to vagal blocking it and may result in paradoxical high degree AV block or sinus arrest.
Atropine
This prohibits intake of certain drugs and protects the brain and spinal cord from toxic substances. It also supplies nutrients and filters harmful compounds from the brain back into circulation.
Blood brain barrier