Disorders of Immune Response
Most common type of hypersensitivity disorder; triggered by binding of allergen to IgE
What is Immediate (type 1) Hypersensitivity
The receptors involved with "rest and digest"; mediate responses to Ach
What are cholinergic receptors
MoA of Cabapenems
What is weakens the cell wall
Mediates responses to Epi and NE
What are Adrenergic receptors
Drug used prophylacticlly for "dirty" surgeries and can cause darkening of urine
What is Metronidazole
An example of an antibody mediated hypersensitivity disorder
Myasthenia Gravis
The drug used to determine the difference between a cholinergic or myasthenic crisis.
What is Tensilon
Can cause teeth staining and is avoided being taken with Ca2+ and food.
What are side effects of Tetracycline
Receptors located in lungs, heart, skeletal muscles, and uterus
Where are B-2 receptors located
Drug that weakens the cell well without a B-lactam ring
What is Vancomycin
Distinguishes Ab-mediated from immune-complex mediated hypersensitivity
What is the binding of the Ig to the cell (Ab-mediated) vs. Ab-Ag complexes
Neuromuscular blockers used for short-acting paralysis/ procedures
What are Depolarizing n-m blockers
Reserved for MRSA and VRE because side effects include Myelosuppression
What is the use of Linezolid
Activation of these causes mydriasis, vasoconstriction, contraction of bladder
What is activation of alpha-1 receptors
TB test and poison ivy are examples of this type of reaction
An example of a 1st generation H-1 receptor blocker
What is Diphenylhydramine, Promethazine, or Hydroxyzine
Hormone responsible for alpha-1, alpha-2 and Beta-1 agonization
What is norepinepherine
Preferred type of dosing because of washout.
Considered indirect acting cholinergic agonist.
What is the summary of action for Cholinesterase inhibitors
When donor and host have very different types of cells and the donor cells attack the host
What is Graft vs. Host Disease
The 3 mechanisms involved in Ab-mediated reactions
What are cell destruction, Ab-mediated inflammation, and cellular dysfunction
Adrenergic receptors responsible for dilation of renal vasculature
What are dopamine receptors
Patient must stay hydrated because can cause kidney/bladder stones
What is nursing education when taking Sulfamethoxale-trimethroprim (Bactrim)
Highly selective drug; only works on B-2 receptors
What is the target of Albuterol
Drug class that works well with aminoglycosides
What are Penicillins