Potpourri of Problems
Prior to 20 weeks gestation, the fetus is dependent on placental transfer of this thyroid component.
What is T4 (thyroxine)
In maternal myasthenia gravis, these antibodies cross the placenta to cause fetal disease
What are Anti-AChR antibodies? (acetylcholine receptor)
These types of antibodies cause fetal injury in the setting of maternal lupus.
What are anti-Ro and anti-La antibodies?
Trauma related complications of pregnancy include: placental abruption, preterm delivery, and this outcome.
What is spontaneous rupture of membranes?
These classes of cardiac medications need to be held during pregnancy due to teratogenicity.
What are ACEI and ARBs?
This common obstetric drug should not be given to mothers with myasthenia gravis.
What is magnesium?
True or False: the majority of babies with fetal heart block 2/2 anti-Ro/La antibodies are born to moms with known autoimmune disease.
What is false? Only 50% of mothers have a known diagnosis of autoimmune disease.
High Injury Severity Score, serious abdominal injury and hemorrhagic shock all increase the risk of this.
What is fetal loss?
When a mother has cyanotic heart disease, these 2 physiologic compensations can be made to preserve oxygen delivery to the fetus.
What are increased fetal hemoglobin and rightward displacement of the oxygen dissociation curve?
This is the length of time an infant should be monitored after birth for signs of transient myasthenia if their mother has known myasthenia gravis.
What is 48-72hr?
For infants of mothers with ITP, platelet counts below this threshold should be treated with IVIG.
What is 20K?
A pregnant woman at 36 weeks is in a MVA and presents to the ER with abdominal pain. This is the fetal heart rate tracing, which is concerning for this problem.
What is a sinusoidal heart rate tracing, concerning for severe anemia, impending fetal demise?
This medication for maternal hyperthyroidism is associated with cutis aplasia if exposure occurs during the first trimester.
What is methimazole?
This medication is preferred for mothers that need anticoagulation during pregnancy.
What is heparin?
In the case of maternal ITP, this is the best predictor of severe thrombocytopenia in the infant.
What is a prior sibling with thrombocytopenia?
Compensated maternal hypovolemia is first manifested by this change in blood flow.
What is decreased placental perfusion?
This fetal outcome is common for chronic maternal diseases that result in hypoxia or impaired placental blood flow.
What is low birth weight/IUGR?
The risk of these congenital malformations are increased with exposure to Valproic acid during pregnancy.
What are spina bifida, ASD, cleft palate, hypospadias, polydactyly, and craniosynostosis?
This is the risk for heart block in future pregnancies if a mother has a history of a child with heart block due to anti-Ro/La.
What is 16%?
The risk is 2% in general for mothers with anti-Ro/La antibodies.
If not due to direct fetal injury or maternal fetal hemorrhage, fetal hypoxemic injury is caused by this.
What is uteroplacental compromise?