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Hematology
Cellular Injury
Immune System
Cancer
100

Which of the following containers of water would have the highest concentration of table salt?

A glass with 100mL of water and 50 grams of salt

A glass with 500mL of water and 2,000 grams of salt

A glass with 50mL of water and 10 grams of salt

What is a glass with 500 mL of water and 2,000g of salt?

100

Which hormone produced by the kidneys produced RBCs?

Erythropoietin 

100

What are the differences between atrophy, hypertrophy, and hyperplasia?

Atrophy - decrease in size of cells

Hypertrophy - increase in the size of cells

Hyperplasia - increase in the number of cells

100

Describe the components of and differences between natural (innate) and adaptive (acquired) immunity.

Innate - born with these (skin, eyelashes, cilia in respiratory tract, mucous, etc)


Adaptive - develops over time (T lymphocytes, B lymphocytes, vaccines, breastfeeding)

100

What impact does smoking have on the development of respiratory infections? Cancer?

Paralyzes cilia, causes chronic inflammation, introduces carcinogens and free radicals into body

200

How does the body regulate fluid volume?

What is the Renin-Angiotensin-Aldosterone System?

200

What is the definition of anemia?

Low RBCs and/or low hemoglobin and hematocrit

200

What is metaplasia and why would this occur?

One cell type replaced by another type due to environmental changes

i.e. GERD

200

What are the symptoms of inflammation and why/how do they occur?

SHARPS

Mast cells releases histamine --> increased permeability and vasodilation

200

Why are we concerned with the development of clostridium difficile when a patient is on antibiotic(s)?

Antibiotics kill intestinal flora; some intestinal flora is good for intestines 

300

Which hormones are involved in regulating fluid volume?

Anti-diuretic hormone, aldosterone

300

Which of these types of erythrocytosis/polycythemia would most likely result from chronic pulmonary disease in which oxygenation is an issue?

Relative polycythemia

Primary polycythemia

Secondary polycythemia

Secondary polycythemia

300

What is neoplasia? 

New cellular growth, aka tumor
300

Describe the difference between nosocomial and opportunistic infections.

Nosocomial - occurs in hospital setting

Opportunistic - r/t decreased/weakened immune system

300

What does consolidation on a chest x-ray indicate? The actions of what type of WBC could cause this?

Pneumonia; mast cells releasing histamine 
400

What possible effects does dehydration have on BUN, Hemoglobin, and Hematocrit?

BUN - increased

Hematocrit - increased

Hemoglobin - increased

400

Thrombocytopenia would be diagnosed if the patient had a:

Platelet count of 240 x 103/mm3

WBC count of 18 x 103/mm3

WBC count of 6 x 103/mm3

Platelet count of 90 x 103/mm3

Platelet count of 90 X 103/mm3

400

What is the most common cause of cellular injury?

Lack of oxygen (hypoxia)

400

How do immunizations work? What type of immunity do they provide?

Infection is introduced to the body and antibodies are formed; active acquired immunity

400

Why/how does cachexia occur in a patient with cancer?

Severe form of malnutrition; WBCs release mediators that break down fat and muscle

500

Explain the difference between the intracellular space, the extracellular space, and the interstitial space. 

Intracellular - inside cell

Extracellular - outside cell

Interstitial - between cells

500

This type of anemia would likely exhibit a low MCV, low MCHC, and high RDW:

Hemolytic anemia

Blood loss anemia

Pernicious anemia

Iron deficiency anemia

Iron deficiency anemia

500

What are free radicals?

Molecules produced as a result of energy production in the cell (which causes inflammation and oxidative stress)

500

What is the difference between inflammation and infection?

Inflammation - immune response to remove injurious agent and protect against infection

Infection - occurs when bacteria or virus enters the system and immune system is not able to fight it

500

What happens during Tumor Lysis Syndrome and why is it a medical emergency?

Cancer causing cells breakdown at a very quick rate and release their products into bloodstream --> kidneys cannot filter properly, which can lead to hyperkalemia, hypocalcemia, hyperphosphatemia

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