Hormone Basics
Gs-coupled receptors raise this second messenger.
What is cAMP?
The anterior pituitary develops from this ectodermal pouch.
What is Rathke’s pouch?
The adrenal medulla arises from this embryological tissue.
What is neural crest?
This is the commonest cause of hypopituitarism.
What is a pituitary tumour?
This animal was recently saved from immediate harm on the side of the road near curtin
What is a Chicken?
This posterior pituitary hormone acts on V2 receptors to insert aquaporin-2 into the collecting duct.
What is ADH (vasopressin)?
Chiasm compression by a macroadenoma causes this visual field defect.
What is bitemporal hemianopia?
This cortical zone makes cortisol and has foamy, lipid-rich cells in straight cords.
What is the zona fasciculata?
In hypopituitarism from a mass, this axis is usually lost last.
What is ACTH (the adrenal axis)?
This 5 letter word can precede Branch, Green, and Garden
What is Olive?
This is the only anterior pituitary hormone under tonic inhibition, by dopamine.
What is prolactin?
Name the commonest functioning pituitary adenoma and its first-line drug.
What are a prolactinoma and cabergoline?
This is the commonest cause of Cushing’s syndrome overall.
What are exogenous glucocorticoids?
Primary but not secondary adrenal insufficiency causes this skin sign, because ACTH is high.
What is hyperpigmentation?
when you change one letter in this companions name, you get a common kitchen appliance
Who is Oven David Milford?
Cortisol has this action on catecholamines, which is why deficiency causes hypotension.
What is permissive?
This GH receptor antagonist is monitored using IGF-1, not GH.
What is pegvisomant?
In Conn’s syndrome, blood pressure is high, renin is low and serum levels of this ion are low.
What is potassium?
In hypopituitarism, replace this before thyroxine to avoid precipitating a crisis.
What is glucocorticoid (hydrocortisone)?
This Number is the total number of reels Abdul has sent to the PBL group chat (+/-1)
What is 7? (6-8)
Continuous rather than pulsatile GnRH does this to LH and FSH release.
What is suppresses it (desensitises gonadotrophs)?
Sudden severe headache, visual loss and collapse in a known adenoma: name the condition and the drug to give urgently.
What is pituitary apoplexy, with IV hydrocortisone?
This enzyme deficiency causes most CAH, with raised 17-OH-progesterone.
What is 21-hydroxylase deficiency?
First three steps in adrenal crisis, before test results return.
What are hydrocortisone 100 mg IV/IM, rapid IV saline, and dextrose if hypoglycaemic?
CLOSEST TEAM WINS
the number of minutes spent in PBL this semester (before todays class)
what is 2760?