Treatment for this disorder involves administering colony-stimulating factors (such as filgrastim or pegfilgrastim)
What is neutropenia
100
A patient with this type of hematologic disorder has lab findings of decreased H & H/decreased RBC indices/increased reticulocyte count/ and decreased erythrocyte count
What is Anemia
100
The established treatment for the failure of vital organs
What is organ trasplantation
100
A state if hypercoagulability which is triggered by activation of the clottin cascade with resultatnt generation of exvess thrombin, deposition of fibrin in the microcirculation, and activation of the fibronlytic system
What is Disseminated Intravascular Coagulation-DIC
200
This means "cell eating" and is the first step in host defense
What is phagocytosis
200
Clotting factors I (fibrinogen), II (prothrombin), V, VII, IX, and X are synthesized here
What is the liver
200
Name 3 important nursing interventions in an immunosuppressed patient
What is meticulous personal hygiene/Avoidance of injury/provide meticulous perirectal care/good oral hygiene/control pain/Aseptic technique/Minimize invasive procedures/manipulation of the environment to minimize exposure to organisms/adequate nutrition/alleviate stress
200
The first immunosuppresant agents used in solid-organ transplants
What are corticosteroids
200
This is the primary treatment of DIC
What is treating the underlying disease
300
Specifically modified proteins present in serum and tissue fluids which are capable of selectively reacting with inciting antigens
What is immunoglobulins
300
The administration of this fluid portion of blood is indicated when there is a coagulopathy or hypovolemia with little of no actual blood loss (burns/crushing injuries)
What is fresh frozen plasma
300
One of the most commonly seen infections in patients with acquired immunodeficiency syndrome
What is Pneumoncystis jiroveci pneumonia (PCP)
300
When these types of lymphoctes recognize foreign antigens, there is a risk for graft rejection
What is T and B lymphocytes
300
Name three physical manifestations which you may see with a patient who has DIC
What is petechiae, purpura, eccymoses, oozing of blood from injection sites/IV lines/and invasive monitoring lines
400
Name the two pathways of the normal coagulation process
What is extrinsic (tissue vascular injury) and intrinsic (vascular injury)
400
Name 1 subjective sign/symptom of hematologic/immunologic disease and 3 objective signs/symptoms of hematologic/immunologic disease
What is fatigue/dyspnea/and inability to perform activities of daily living (subjective) ....and altered mental status/fever/tachycardia/hypotension/tachypnea/cough/dysrhythmia
400
This is the major cause of morbidity and mortality in the patient with leukemia
What is Infection
400
All transplant recipients must take immunosuppresive medications to try to prevent rejection of their new organ. Name the two types of immunosuppression recognized
What is induction immunosuppresion and maintenance immunosuppresion
400
This is a thrombocytopenia which may be due to an autoimmune response with antibodies against platelets developing
What is idiopathic thrombocytopenia purpura (ITP)
500
RBC production is stimulated by the hormone erythropoietin. Erythropoietin is released by the kidney in response to what?
What is tissue hypoxia
500
Name the four major reactions to blood and component therapy
What is circulatory overload/a bacterial reaction (most common -demonstrates a fever)/allergic reaction/and hemolytic reaction(happens within 30 minutes of the transfusion)
500
Describe the stages of Hodgkin's and NonHodgkin's disease
What is Stage I (early disease), Stage II (locally advanced disease), Stage III (advanced disease), and Stage IV (widespread or disseminated disease)
500
A macrolide which inhibits T-cell funtion by preventing synthesis of IL-2 and other important cytokines
What is Tacrolimus (FK-506)
500
Name 3 effective treatments in thrombotic thrombocytopenic purpura (TTP)
What is plasmapheresis, corticosteroids, immunosuppresion, and splenectomy which may prevent subsequent relapses