random
Antihistamines decrease capillary permeability and therefore ________.
edema (wheal)
Why should diarrhea always be taken seriously but antidiarrheals should not be first line of treatment?
symptom of underlying disease that needs to be treated, then judicious use of antidiarrheals
Which movie popularized the phrase “wax on, wax off”?
The Karate Kid
Due to anticholinergic effects, some first generation H1 antagonists such as can be used to treat ________ ________.
motion sickness
Constipation is defined as decreased frequency, but also difficulty in initiation or passage of firm or small-volume feces or a feeling of ________ __________.
incomplete evacuation
T/F: Therapeutic uses for metoclopramide include antiemetic for cancer chemotherapy, persistent hiccups, and gastroparesis.
T, although it is no longer considered a first line antiemetic treatment for cancer chemotherapy
What is the significance of the chemoreceptor trigger zone being located outside the BBB?
What is the term for a baby goat?
Kid
Which category of drugs removed formed uric acid from the blood?
Uricases
What is another name for a "wheal and flare" reaction?
Triple Response of Lewis
Why should antibiotics be avoided in patients with suspected or proven enterohemorrhagic E coli?
because of the risk of hemolytic uremic syndrome (HUS)
T/F: Serotonin 5-HT3 antagonists should not be administered to patients with shortened QT interval or in conjunction with other medications that shorten the QT interval.
F, serotonin 5-HT3 antagonists have small but statistically significant prolongation of the QT interval, so should not be administered to patients with prolonged QT or in conjunction with other medications that may prolong the QT interval
Which type of edible fungus is considered a delicacy and often compared to diamonds?
Truffle
Which drug used to treat RA is a salicylate?
Sulfasalazine
What properties of may lend to second gen H1 antagonists being more effective in the topical treatment of allergic conjunctivitis?
Second gen H1 antagonists exhibit mast cell-stabilizing effects, resulting in reduced release of mast cell mediators during an allergic response
Why are lorazepam or diazepam sometimes used before the initiation of chemotherapy?
to reduce anticipatory vomiting or vomiting caused by anxiety
How does histamine binding to the H2 receptor on the parietal cell lead to acid secretion?
Activation of adenylyl cyclase, which increases intracellular cAMP and activates protein kinases that stimulate acid secretion by the H+/K+-ATPase
Which music video by OK Go featured an elaborate choreographed routine on treadmills in 2006?
"Here It Goes Again"
What are the four CNS adverse reactions associated with tacrolimus?
1) headache
2) tremor
3) insomnia
4) paraesthesia
What highly lipid-soluble compound has been used in as a prophylactic antiemetic agent in patients receiving cancer chemotherapy, and has found use in patients with anorexia?
Cannabinoids
Why is castor oil not recommended at all as a therapeutic option?
it is a source of an extremely toxic protein- ricin
What is the MOA of docusate?
It is an anionic surfactant that alters surface tension of the stool, allowing mixing of water, lipids, and other fecal matter. Also alters intestinal permeability, which increases net water and electrolyte secretion.
What is the name of the famous painting by Edvard Munch depicting a figure with a distorted face?
The Scream
Which patients should not use probenecid?
patients with kidney stones or impaired renal function
This medication is a specific 5HT4 receptor agonist that acts throughout the length of the intestine and is used in treatment of adult women younger than 65 with IBS-C.
Tegaserod (Zelnorm)