Sickle Cell
What shape does the red blood cell take in sickle cell?
What is sickle shaped?
True or False: It is an autosomal recessive trait
What is True?
True or False: This hereditary blood disorder has a cure
What is false?
Test that measures the Von Willebrand factor
What is Elisa?
True or False: Leukemia is abnormal proliferation of immature white blood cells
What is True?
How long does it take for symptoms to present?
What is 4-6 months?
Therapy that decreased iron concentration in the liver
What is Chelation Therapy?
Name a lab test for diagnosis
What is PT, PTT, PLT, bleeding time, fibrinogen?
Name 2 signs or symptoms of the disease
What is bleeding gums, prolonged bleeding from cuts, excessive post-op or menses bleeding, history of epistaxis?
Name 2 symptoms of leukemia
What is low-grade fever, pallor, increased bruising/petechiae, listlessness, enlarged liver/lymph nodes/joints, headache, constipation, abdominal/leg/joint pain
True or False: Growth in puberty is not affected
What is false?
What is excessive iron?
Is hemarthrosis a mild, moderate, or severe manifestation?
What is moderate?
Name the factor the Von Willebrand disease carries
What is Factor VIII?
Name 2 out of 4 diagnostic procedures
What is bone marrow aspiration, lumbar puncture, flowcytometry, liver and kidney function studies?
Name the three forms of sickle cell crisis
What is vaso-occlusive, acute splenic sequestration, aplastic?
Name the only cure
What is bone marrow transplant?
Name the medication given for nosebleeds
What is aminocaproic acid/tranexamic acid?
Name the treatment of choice.
What is DDAVP?
After a CFS analysis how many hours do you need to lie in a flat position to prevent leakage?
What is 4-8 hours?
Name the drug of choice for pain in sickle cell disease
What is Morphine?
Name 3 long-term manifestations.
What is enlarged head, prominent and protruding forehead, wideset eyes, and flattened nose
Name the prophylactic treatment in infants with severe disease to preserve joints
A nasal spray/desmopressin acetate
What two lab values do you need to be concerned with?
What is PTT and bleeding time?
Name the three phases of chemotherapy
What is induction therapy, consolidation therapy, and maintenance therapy?