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Delayed, non-suppurative sequela of infection with group A beta-hemolytic streptococci or Streptococcus pyogenes. The acute phase of ARF (acute rheumatic fever) is caused by a proliferative inflammatory reaction that involves the connective and/or collagen tissues and commonly affects the heart, joints, brain and subcutaneous tissues, although any organ may be involved.
Name the major criteria for ARF
What is Joint involment, Heart involvment (Pericarditis, effusions to heart), Bodules, Erythema marginatum, Sydenham's Chorea.
Minor criteria: High CRP/ESR, fever, arthralgias, and prolonged PR interval.