What were the two trials that were included in the NEJM article?
1. Aegis I
2. Aegis II
100
He/She nickname is J-Bear and was born in Salt Lake City, Utah.
Who is Jackson
100
1) What are our 3 key messages for Percepta?
a. Accurate and actionable, informing which patients may
be considered for CT surveillance
b. Clinically proven in over 1000 patients
c. Fits easily in your daily practice
100
What was the name of the product before it was called Percepta?
What is bronchogen
100
How many patients were in the "intermediate risk" category?
101 patients
200
What was the total number of patients in Aegis I and II trials?
639 patients
200
He/She was born inWarwick, RI and one of their nicknames is Kieliszak
Who is Jessica
200
In the Aegis trials when were the Percepta brushing collected during the procedure?
B. Before other biopsies
200
How was risk categorized/grouped in the Aegis I and II trials
What is:
2. Less than 10%; Between 10 - 60%; Over 60%
200
What was the negative predictive value (NPV) of the test in the intermediate patient population with a non-diagnostic bronchoscopy?
91 % NPV
300
What was the non diagnostic rate (%) of bronchcoscopy?
43%
300
He/She was born in Edna, MN and their nickname is Bananas.
Who is Jon Ulvestad
300
Which categories of pre-test risk patients is there the primary utility of the test?
D. Intermediate and low
300
In the Aegis trials, what were the Percepta results independent of ?(ie location)
What is lesion size, location, cancer type, and stage
300
How many centers participated in the study?
28 centers
400
What was the publication date of the article (month is fine)
May 17th, 2015
400
He/she was born in South Bend, IN and their nickname is Ghost.
Who is Eric Kovatch
400
What is turn around time (from time of order)of the test?
A.5-10 days
400
How many genes make up the Percepta test?
What is 23 genes?
400
What were the two conclusions of the article?
1.The GEC improved the diagnostic performance of the bronchoscopy for the detection of lung cancer.
2. In intermediate risk patients with a non dx bronchcoscopy, a negative classifier score provide support for a more conservative diagnostic approach
500
Who were the 1st 3 authors on the article?
Gerard Silvestri, Anil Vacani, Duncan Whitney
500
He/she was born in Wurzburg, Germany and their nickname is Spike?
Who is Chet Galek
500
Please verabalize the messaging around the cost of the test?
a.Veracyte is absorbing cost of Percepta until sufficient evidence for payor coverage (mid 2016). Medicare reimburses 3200 for Afirma.
500
What risk calculator was used to assess risk in the Aegis trials?
What is no risk calculator was used or physician assessed risk
500
The 28 sites were represented by 3 different countries? Name those countries.