Definitions
What is half- life?
The time it takes for 50% of the drug to be eliminated from the blood stream
What does ADME stand for?
Absorption, Distribution, Metabolism, Excretion
ii caps q12h ud
Take two capsule by mouth every 12 hours as directed
Oral
What are the 5 sources of drugs
Natural, Synthetic, Semisynthetic, Minerals, Plants/Animals
What is the definition of Pharmacotherapy?
The use of drugs in treatment for disease
What is MDI?
Metered-Dose Inhaler
1 gtt ou ud x 7D
Instill 1 drop into each eye as directed for seven days
What is the name of the tablet that is meant to release its contents in the intestine?
Enteric Coated
What are the 2 branches withing Pharmacology
Pharmacodynamics and Pharmacokinetics
What is first pass effect?
What does ROA stand for and give 3 examples?
(Bonus 200pts if you can name five)
Route of Administration
Oral, Topical, Intravenous, Intramuscular, Eye/Ear
d/c aspirin 10d pre op
discontinue aspirin 10 days before operation
What is the final dosage form of an ointment?
Semi-solid preparations
Who discovered insulin?
Banting and Best
What is a prodrug?
An inactive drug form that the body metabolizes into an active drug form
What is NOC?
(Drug companies must obtain this)
Notice of Compliance
Available drug: zopiclone 7.5mg tab
3.75mg hs prn
take one half of a tablet at bedtime as needed
What are the ROA sites for suppository?
Rectally, Vaginally, Urethral
What must a drug manufacturer get before they can start processing their drug?
Patent
What is the drug property that controls chemical and human physiology?
Drug Formulation
(Bonus pts if you know how many digits must be in a DIN)
Drug Identification Number
8
i tab qam, 2 tab hs ud
take 1 tablet by mouth every morning then 2 tablets at bedtime as directed
What is a osmotic controlled capsule?
A capsule that contains small pin holes in the shell
(to distribute the dosage at multiple sites)
What is drug Nomenclature
Brand(trade), Generic, Chemical