Succinylcholine Essentials
What is the DOA of succinylcholine
4-6 min
This electrolyte abnormality occurs due to potassium release from muscle cells.
hyperkalemia
Patients with burns >24 hours old are at risk for this complication.
Severe hyperkalemia
This nondepolarizer is preferred for RSI when sux is contraindicated.
Rocuronium
This reversal drug is dosed at 50–70 mcg/kg and must be given with glycopyrrolate.
Neostigmine
What is the intubating dose of succinylcholine?
1-1.5 mg/kg
This postoperative complaint is caused by muscle fasciculations.
Myalgia
This type of injury leads to massive K⁺ release due to receptor upregulation.
crush injuries or severe trauma
This drug is best in renal or hepatic failure due to Hoffman elimination.
Cisatracurium
This reversal agent works fastest and has onset in 30–60 seconds.
Edrophonium
This phase of block is characterized by no fade and sustained depolarization.
Phase 1 block
This life-threatening condition is triggered by succinylcholine and volatile agents.
MH
This condition involving nerve injury or immobilization increases extrajunctional receptors.
denervation or prolonged immobilization
This drug causes histamine release and should be avoided in asthmatics.
Atracurium
This drug reverses rocuronium and vecuronium by encapsulation.
Sugammadex
This phase of block begins to resemble nondepolarizing blockade and shows fade.
Phase 2 block
This pressure is increased after administration and is important in eye trauma.
IOP
This neurologic condition (autoimmune demyelinating) increases potassium risk.
Guillain-Barré syndrome
This long-acting NMBD increases heart rate due to vagolytic effects.
Pancuronium
A TOF of 2 twitches corresponds to approximately this % blockade.
~80% blockade
This enzyme is responsible for metabolism of succinylcholine.
plasma cholinesterase (pseudocholinesterase)
This cardiac effect is most common after a second dose within 5 minutes.
Bradycardia
This neuromuscular disease makes succinylcholine especially dangerous in pediatrics.
Duchenne muscular dystrophy
This intermediate NMBD has active metabolites that accumulate in renal failure.
This monitoring site is best for determining recovery prior to extubation.
ulnar nerve (adductor pollicis)