MOA
ADR
Contra-indications
Drug class
Clinical clues
100

What is the mechanism of action of beta-blockers like metoprolol?

What is inhibit beta-1 receptors to decrease HR and contractility

100

What common opioid side effect requires fall precautions?

What is sedation/drowsiness. 

100

Which drug classification might be contraindicated in asthma patients?

What is a non-selective beta-blocker. 

100

Lisinopril

What is an ACE inhibitor

100

Patient on amlodipine has ankle swelling. Cause?

What is peripheral vasodilation. 

200

How do statins lower LDL cholesterol?

What is inhibit HMG-CoA reductase.

200

Which drug class causes dry cough and angioedema?

What are ACE inhibitors. 

200

Why are anticoagulants contraindicated after hemorrhagic stroke?

What is an increased risk of hemorrhage. 
200

Warfarin

What is an anticoagulant/vitamin K antagonist

200

Patient on metoprolol has exercise fatigue. Cause?

What is a blunted sympathetic response. 

300

Which enzyme do ACE inhibitors block?

What is Angiotensin-converting enzyme. 

300

Statins are associated with which muscular side effect?

What is myopathy. 

300

Which of the following patient presentations would require the physical therapist to hold therapy and refer immediately due to a potential contraindication of a CHF medication?

What is Patient on digoxin with new-onset irregular pulse and confusion

300

Amlodipine

What is a calcium channel blocker

300

During a therapy session, a patient with CHF on high-dose furosemide reports new-onset muscle cramps, fatigue, and an irregular heartbeat. What is the most appropriate action for the physical therapist?

What is suspect hypokalemia and refer to the medical team.

400

What drug class works by enhancing antithrombin III?

What is Heparin. 

400

Which vital sign does a beta-blocker blunt during exercise?

What is heart rate. 

400

What condition is a contraindication for statins due to hepatotoxicity risk?

What is active liver disease. 

400

Atorvastatin

What is a HMG-CoA reductase inhibitor (statin)

400

CHF patient on furosemide reports dizziness. Why?

What is orthostatic hypotension. 

500

What is the MOA of digoxin?

What is inhibits Na+/K+ ATPase → ↑ intracellular Ca²⁺

500

Furosemide may cause what electrolyte imbalance causing cramps?

What is hypokalemia. 

500

This medication used for heart failure and atrial fibrillation becomes contraindicated when a patient develops significant renal impairment, due to its narrow therapeutic index and risk of toxicity.

What is digoxin. 

500

Enoxaparin

What is a low molecular weight heparin (LMWH). 

500

This electrolyte disturbance, common in patients taking both furosemide and digoxin, increases the risk of life-threatening arrhythmias and should be suspected if a patient develops fatigue, weakness, or irregular pulse during therapy.

What is hypokalemia. 

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