Med Basics & Delivery Systems
Oil in a water emulsion is called what?
Cream
Which BRM for psoriasis is a PDE-4 inhibitor?
Aprimilast
ID 2 differences between IM and SQ administration
Angle & volume
The 3 high potency TCS
1. Halobetasol
2. Clobetasol
3. Betamethasone
If I prescribe a patient a prodrug and the result is increased toxicity, what kind of metabolizer are they?
ultrarapid
This receptor binds to a component of a receptor complex AND blocks the activation of a 2nd component
Agonist-antagonist
Which oral medication for onychomycosis can cause serious hepatic toxicity?
Fluconazole
Which 2 medications continue to have a therapeutic effect for many weeks after cessation of the drug?
Itraconazole & terbinafine
ID 3 benefits of transdermal administration
Less invasive, no first-pass, prolonged infusion time, pt adherence
How do I need to adjust dose of a medication if their albumin is too high?
Increase dose
Least & most absorbed body sites for topical costicosteroids
soles of feet & scrotal skin
You want to space taking this medication with eating dairy
Tetracylcine
Identify two medications associated with photosensitivity
Sunscreen, isotretinoin, permethrin, benzyl peroxide
Name the 3 processes of metabolism
Activate
Inactivate
Make polar
These 2 values are always in opposition in regards to drug circulation
half life & clearance
These 2 types of medication administration always goes through the tissues before getting to the circulatory system
SQ & IM
This medication has a contraindication of soybean
Identify two similarities between Isotretinoin and Acitretin
Retinoid analog
Preg X warning
Name the 3 phenotypes for drug transporters
Normal function
Intermediate function
Low function
The genotype of an enzyme with 2 no-function alleles is called what?
poor metabolizer
This type of oral formulation may cause initial toxicity in the form of side effect but quickly backs off
Immediate Release (IR)
This medication class has a black box warning about correlations to lymphoma
Calcineurin Inhibitors
Two PDE-4 inhibitors are
Crisaborole & Aprimilast
The 3 physical blocking agents to sun are:
Titanium dioxide
Zinc oxide
Calamine
What happens to Vd if the patient has kidney failure?
Increases