Random
Which drug is used to treat Myasthenia Gravis and prevent postoperative urinary retention?
Neostigmine
Which drug is known as a mixed α/β direct agonist and is referred to as 'The Do Everything Drug'?
Epinephrine (Adrenaclick)
What is the drug used to produce miosis in ophthalmic surgery?
Acetylcholine
ppt. 20
Where is the location of the ganglia in parasympathetic/sympathetic division?
parasympathetic-in visceral organs
sympathetic- close to spinal cord
What is a common side effect of Prazosin (Minipress) upon its first administration?
First-dose orthostatic hypotension
Which nonselective β + α₁ blocker provides a mortality benefit in HFrEF and has antioxidant properties?
Carvedilol (Coreg)
What visual sign occurs before paralysis when Succinylcholine is administered?
Fasciculations
Which drug is used topically in open angle glaucoma patients who have become tolerant to pilocarpine?
Carbachol
ppt. 20
If fibers are parasympathetic, the lengths will be _____pre &____post ganglionic
If fibers are sympathetic, the lengths will be _____pre &____post ganglionic
long pre & short post
short pre & long post
If atropine is given at a dose of 10mg or higher (high dose) what could be some adverse effects?
Hallucinations, delirium, coma
Which drug is specifically used for hypertensive emergencies in pregnancy?
Labetalol
How do the effects of Epinephrine change based on dosage?
Low doses favor β effects, while high doses cause α effects to predominate.
Which drug treats open angle glaucoma, binds at muscarinic receptors, and is ALSO known for its ability penetrate the CNS?
Pilocarpine
ppt20
If fibers are parasympathetic they will originate from where?
If fibers are sympathetic they will originate from where?
Brain & Sacral Spinal cord
Thoraco-Lumbar Spinal cord
What is a contraindication of atropine usage?
Narrow angle glaucoma
Besides hypertension, what are two other conditions Prazosin is used to treat?
BPH (Benign Prostatic Hyperplasia) and PTSD nightmares
What makes Phenylephrine (Neo-Synephrine) unique compared to other adrenergic agonists?
It is a pure vasoconstrictor with no β activity, meaning it provides no direct cardiac stimulation.
Which drug is known to increase intestinal/bladder motility and is also used because it can cross the BBB and reverse the effects of Atropine?
Physostigmine
Which of the following is expected outcome of parasympathetic activation of the heart?
Decreased rate, decreased contractility
Patients with this condition may have adverse effects when taking Propranolol. What is the condition, and why?
It is a non-selective β-blocker that blocks and receptors to blunt the racing heart, tremor, and sweating of anxiety; because it blocks receptors, it should be avoided in patients with asthma.
What are two major risks associated with Succinylcholine administration?
Hyperkalemia and Malignant Hyperthermia
What is the mechanism of action for Clonidine (Catapres)?
It is a centrally acting α₂-selective agonist.
What is the D.U.M.B.E.L.S or S.L.U.D.G.E & killer B's acronym used for and what does either one stand for?
Symptoms of cholinergic crisis!
Diaphoresis/Diarrhea. Urination. Miosis. Bradycardia/Bronchospasm/Bronchorrhea. Emesis. Lacrimation. Salivation (DUMBELS)
Salivation.Lacrimation.Urination.Diaphoresis/Diarrhea.Gastrointestinal cramping.Emesis.Bradycardia/Bronchospasm/Bronchorrhea
Which of the following is expected outcome of sympathetic activation of the trachea and bronchioles?
Dilation
Why must Phenoxybenzamine be given before β-blockers in patients with pheochromocytoma?
To prevent an unopposed α-mediated vasoconstriction which could lead to a hypertensive crisis.