The site of activation for all Autonomic preganglionic fibers
What is a nicotinic receptor?
100
Drugs can be administered in 3 different physical states
What is solid, liquid, gas?
100
Beta blockers are widely used to treat this disease of the eye.
What is glaucoma?
100
When Norepinephrine is released there will be no activation on this receptor.
What is Beta-2 adrenergic receptor
100
Is sometimes defined by the phrase "How the body acts on a drug"
What is Pharmokinetics?
200
Receptors can be categorized into four types.
What is Nucleic acid, Intracellular protein, transmembrane and enzyme
200
This method of drug interaction is the strongest and longest-lasting. Remains bound until new receptors are synthesized.
What is Covalent bond?
200
Causes the following effects on muscarinic receptors: lacrimation, mitosis, diarrhea, urination, bronchoconstriction, excitation of skeletal muscle, salivation
What are cholinergics?
200
DAILY DOUBLE:This Direct agonist of acetylcholine receptors, used in treatment of Wide Angle Glaucoma is not susceptive to Acetylcholinesterase degradation.
What is Carbachol?
200
The concentration of a drug at 50% of its original value
What is half-life?
300
The site of activation for epinephrine released from adrenal medulla.
What is nicotinic receptor (N2)?
300
This route of administration has 100% bioavailability
What is intravenous?
300
This type of poisoning is caused by mushroom species Inocybe.
What is muscarine poisoning?
300
This type of drug response achieves the desired effect with no side effects or toxic effects
What is Therapeutic response
300
Works by a two step process to metabolize acetylcholine
What is acetylcholinesterase?
400
This general class of adrenergic antagonists includes orthostatic hypotension as a side effect.
What are Alpha-1 adrenergic antagonists? Example: Prazosin, Terazosin, tamsulosin
400
The major site of excretion of drugs
What is the kidney or Renal system?
400
Activation at this adrenergic receptor by an antagonist can mask diabetic hypoglycemia due to inhibition of glycogenolysis. This could be bad for diabetics.
What is Beta-2?
400
This drug used to treat Myasthenia Gravis has a long duration and is a reversible inhibitor.
What is Pyridostigmine?
400
When a drug is metabolized by the liver prior to reaching target.
What is first-pass?
500
Patients suffering from asthma would be advised not to use drugs acting on these receptors due to their lack of specificity and potential to cause bronchoconstriction.
What are Beta receptors?
500
DAILY DOUBLE: Refers to the the efficiency of delivery to systemic circulation.
What is bioavailability?
500
This type of drug response in patients is rare and unpredictable, observed in even very low doses.
What is idiosyncratic?
500
Reversible Cholinesterase Inhibitors are not recommended for these patients potential for bronchoconstriction
What is asthma/COPD?
500
Individuals suffering from muscarine poisoning will be given this to reverse effects.