Drugs 1
Drugs 2
Vocab
Unit 1:Pharmacology
Unit 2: Respiratory
100
What drug causes a rebound effect?
pseudoephedrine (Sudafed)
100
Treats inflammatory response or severe allergies
prednisone
100
What are the characteristics of a schedule 2 drug?
They are abused and dangerous
100
initial metabolism of drugs, drug is absorbed down in gi tract, but liver enzymes break down most of drug
first pass effect
100
T/F Systemic effects occur primarily with oral agents and they have a rare chance of rebound congestion
True!!
200
Antidote for acetaminophen overdose?
200
side effects include dizziness, hallucinations, sedation
dextromethorphan
200
Angioedema
a condition that causes swelling in the deeper layers of the skin or mucous membranes, and can affect any part of the body. It can be life-threatening if it involves the larynx, making it difficult to breathe and talk.
Angioedema: Symptoms, Causes, Treatment, Types - WebMD
Jul 22, 2023 — Angioedema usually gets better on its own within a few days. If you do need treatment, it can include: Medicines to ea...
WebMD
Angioedema - Symptoms and Causes
Penn Medicine
Angioedema: Causes, Symptoms, Types & Treatments
Puffy or swollen face, especially your eyes and mouth, including lips and tongue. Digestive problems when your intestines are swol...
Cleveland Clinic
- Show alla condition that causes swelling in the deeper layers of the skin or mucous membranes, and can affect any part of the body. It can be life-threatening if it involves the larynx, making it difficult to breathe and talk.
Angioedema: Symptoms, Causes, Treatment, Types - WebMD
Jul 22, 2023 — Angioedema usually gets better on its own within a few days. If you do need treatment, it can include: Medicines to ea...
WebMD
Angioedema - Symptoms and Causes
Penn Medicine
Angioedema: Causes, Symptoms, Types & Treatments
Puffy or swollen face, especially your eyes and mouth, including lips and tongue. Digestive problems when your intestines are swol...
Cleveland Clinic
a condition that causes swelling in the deeper layers of the skin or mucous membranes, and can affect any part of the body. It can be life-threatening if it involves the larynx.
200
the drug entering cells membranes
absorption
200
The more narrow the therapeutic index, the more ________ the drug is.
Risky, this increases the risk of drug toxicity, so start at low doses
300
For long-term suppression of bronchospasms, a patient taking bronchodilators should also take what?
Glucocorticoids like cromolyn or montelukast
300
attaches to beta 2 receptors to reduce bronchial smooth muscle and inhibit histamine release
albuterol
300
teratogenic effect
a drug-induced birth defect
300
this class of drugs has the highest risk for fetal death during pregnancy
x
300
What are the 3 steps to stop an acute asthma attack?
-epinephrine
-albuterol
-glucocorticoids
400
Beta2-agonists suppress _______ release in the lung and __________ ciliary motility.
Histamine, Increase
400
side effects include, v-fib, arithmias, seizures and death from cardio respiratory collapse
theophylline
400
effects when the sum of two drugs is the total of the two drugs when combined
additive effects
400
processes determine how much of an administered dose gets to its sites of action. There are four major processes: (1) drug absorption, (2) drug distribution, (3) drug metabolism, and (4) drug excretion
pharmacokinetics
400
sympathomimetics
reduce nasal congestion
500
How to administer cromolyn (Intal). Give at least 4 instructions.
- Use with a nebulizer or metered-dose inhaler.
- Expect several weeks of use for full effects to become apparent.
- Administer four times daily on a fixed schedule.
- Use the inhaler 15 min before exercising to prevent exercise-induced bronchospasm.
- Do not use to relieve an acute asthma exacerbation.
500
take with a full glass of water
gauifenesen
500
when the sum of the effect is more than the two individual chemical effects combined.
synergistic effects
500
Be especially vigilant when a patient is taking a drug with a low or “narrow” therapeutic index, Ratio of the drug’s LD50 (average lethal dose to 50% of the animals treated) to its ED50
therapeutic index
500
What are the differences between DPI's and MDI's? Which one is easier to use?
- For MDI's take a full breath before puffing and wait at least 1 minute between puffs
-Use a spacer for MDI if needed
-Do not use a spacer for DPI
-Don't crush DPI meds
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