Men's Health
This medication is known to interact with ACE inhibitors and ARBS
HINT: It helps control the overproduction of Testosterone
Spironolactone
This drug is known to treat diabetes insipidus and nocturnal anuresis
Desmopression
This is the broadspectrum antifungal that is highly toxic and used for systemic mycosis
What are some SE of this medication
How would you administer this medication
Amphotericin B
SE: Infusion reactions, nephrotoxic, hematologic effects (thrombocytopenia, leukopenia, leukocytosis, agranulocytosis, and coagulopathy)
Large vein (at least 20 G or PICC line) IV- 6-8 weeks to 3-4 months
This disease is known to be a hypo-adrenal disorder
Name a few s/s
Addison's Disease
Bronze pigmentation, changes in distribution of body hair, GI disturbances, weakness, hypoglycemia, weight loss, etc.
ECG that shows Peaked T-waves is an indicator of what?
Late indicator of Hyperkalemia
What are SE of Testosterone and as the nurse what will you be monitoring?
Hepatitis (Jaundice, LFTs), prostate cancer/ prostatitis (screen), Polycythemia (H/H), lipid panel, CBC, testosterone levels, BMP (SCr, BUN, GFR), 12 Lead EKG baseline
What medication is known to treat Addison's disease? Explain how it does this.
Fludrocortisone
Increases release of aldosterone, Sodium and water reabsorption, excretion of potassium
This Antifungal is used for thrush and is contraindicated in liver failure
Nystatin
What 2 medications interact with Testosterone
Warfarin (increases INR), insulin (can cause hyperglycemia)
This hyper-adrenal disorder is known as
Name some s/s
Cushing's syndrome
Personality changes, moon face, hyperglycemia, increased infections, gynecomastia (males), osteoporosis, etc.
Sildenafil is used for= (What 2 things)
What does it interact with that is also the big contraindication when using this medication?
What is the Drug class?
Pulmonary HTN, ED
NITRATES! (Nitroglycerin)
Phosphodiesterase-5-inhibitor (PDE5)
What is Hypothyroidism?
Give s/s:
List the types:
How do you treat it?
High TSH and low T4
Hair loss, apathy, lethargy, coarse/dry scaly skin, muscle aches, weakness, constipation, intolerance to cold, receding hairline, etc.
Myxedema (adults), Cretinism (children <2 y/o)
Levothyroxine
This broaspectrum antifungal is used for candidiasis infections and has better GI absorption.
What are some SE?
How would you administer?
Fluconazole
Negative inotropic effects, QT prolongation, hepatotoxic
IV, PO, Suspension/pill (eat high fat meals to increase absorption of this medication)
What are the 2 phases of Hepatitis?
Acute phase ( up to 6 months)- Liver inflammation, jaundice, elevated ALTs, typically resolves spontaneously
Chronic phase: Cirrhosis, hepatocellular carcinoma, liver failure, and death
Levothyroxine is dosed in ____ and NOT ____
what is the half life?
Mcg NOT mg
7 days
This medication is used for BPH and kidney stones (in females)
What is the drug class?
What are some SE?
What are some nursing interventions?
Tamsulosin
Alpha-1-adrenergic antagonist
OH, ejaculatory failure
Slow to stand (due to OH), Monitor kidney and liver labs
This medication will be taken when there is a GH deficiency
what is the SE?
Somatropin
Hyperglycemia!
This medication is known to treat Hep B
What would you monitor? How would you educate?
Nucleoside RTI
ALTs/ASTs, if patient is HepB positive test for HIV because HIV requires a higher dosage, repeated interval use can promote resistant HIV strands
SE of this medication include Hepatotoxic, Agranulocytosis, and Hypothyroidism
PTU
This medication is known to treat Hep B (SQ) and Hep C as well by blocking viral entry into the cells
What are some SE?
Interferon Alfa
SE: Flu-like symptoms 50% of the time, neuropsychiatric effects, Depression, SI, fatigue, thyroid dysfunction, bone marrow suppression, GI affects, and injection site irritation
What are some Adverse affects of Hormone therapy?
What are contraindications?
Hormone-dependent cancers (ovarian, breast, vaginal, lung, colon, brain), supra-therapeutic dose (polycythemia/erythrocytosis), sub-therapeutic dose (bone demineralization), decreases HDL, increased triglycerides, and transient transaminitis
Pregnancy, unstable coronary artery disease (increased risk of MI), untreated polycythemia (testosterone will worsen this)
What is Hyperthyroidism?
Give s/s:
List the types:
How do you treat it?
Low TSH and High T4
s/s= Heat intolerance, fine/straight hair, bulging eyes, facial flushing, enlarged thyroid, tachycardia, increases systolic BP, breast enlargement, weight loss, muscle wasting, etc.
Grave's disease, thyrotoxic crises, toxic nodular goiter
What are some SE?
HSV, can also be used for VZV and CMV
More common with IV admin (bone marrow suppression, granulocytopenia, thrombocytopenia, neutropenia, nephrotoxic/neurotoxic, teratogenic/embryo-toxic, phlebitis), abdominal pain, GI bleed, anorexia
TSH= 0.5-4.0
T3= 100-200
T4= 4.5-11.2
Free T4= 0.7-1.5
This medication treats Influenza A and B
What is the drug class?
What are some SE?
Oseltamivir
Neuraminidase inhibitor
Same as the flu: Cough, chills, sore throat, fever, HA, N/V, myalgia