Pharm for
Osteoporosis
Osteoporosis
True or False
Calcium salt should be taken at bedtime
False.
With meals or 1 hour after meals
A client on a calcium salt supplement shold be monitored for which of the following?
a. tinnitus
b. urinary retention
c. kidney stone
d. diarrhea
c. kidney stone
What is the bisphosphonates prototype drug?
alendronate (Fosamax)
What does SERM stand for?
What is Selective Estrogen Receptor Modulator
What does DMARD stand for?
What is Disease-Modifying Antirheumatic Drugs
When should osteoporosis prevention begin?
Early adulthood
What is the most frequent cause of osteomalacia worldwide?
Vitamin D and Calcium deficiency in the diet
The nurse will teach a client prescribed alendronate (Fosamax) that the client must:
a. take with full glass of water
b. not lie down for 60 minutes after taking
c. drink milk to help absorbtion
d. take with or without food
a. take with a full glass of water
What is the prototype drug for SERMS?
What is raloxifene (Evista)
What is the DMARD prototype drug?
What is adalimumab (Humira)
This class of drugs inhibit bone resorption by suppressing osteoclast acitivity, thus increasing bone density and reducing the incidience of fractures by about 50%
What are biophosphonates
What is osteomalacia?
softening of the bones due to demineralization
Calcium supplements have few side effects and do not interfere with other drugs.
True or False?
False
Interactions with Digoxin, magnesium, tetracyclines, and calcium channel blockers.
This medication will slow the progression of rheumatoid arthritis by preventing joint destruction.
adalimumab (Humira)
Name 1 teaching point that is important for a client who is being treated for gout with allopurinol?
-drink 2.5 - 3 liters of water a day
-report rash, fever, and other DRESS sx immediately, stop allopurinol and notify HCP
-take with food or milk
What are 2 examples of nonpharmacologic strategies while taking calcium salts for a client at risk for osteoporosis?
-Eliminate excessive soda
-include daily activity and exercise
-obtain adequate sun exposure
The client has osteomalacia, the HCP prescribes a treatment to restore calcium balance. What is the best combination the nurse should give this client?
What is calcium supplements and Vitamin D
Common side effects of alendronate (Fosamax) frequently involve this body system.
GI system
A nurse is teaching a client taking Evista how to prevent blood clots What would be advised during travel on a long flight or car ride?
The nurse should advise the client to walk as much as possible.
What is the purpose of allopurinol (Zyloprim) for gout?
Inhibition of the formation of uric acid.
Name 3 major risk factors for osteoporosis.
menopause, increasing age, family h/o osteoporosis, excessive alcohol, smoking, immobility/inactivity, Caucasian or Asain race, gonadal hormone deficiency, Low vitamin D or calcium in diet; drugs (corticosteroids, some anticonvulsants, and immunosuppresants)
What assessment in a patient receiving calcitrol should the nurse report immediately to the HCP?
Signs of hypercalcemia: Bone pain, lethargy, anorexia, nausea, vomiting, increased urination, hallucinations, and dysrhythmias
Name 2 of the 3 subtances that are essential in Bone homeostasis? Together they regulate the absorption and excretion of calcium.
PTH, calcitonin, and Vitamin D
Mary has osteoporosis and is prescribed ralozifene (Evista) What history could put her at risk for complications?
a. h/o PUD
b. h/o abnormal breat biopies
c. h/o blood clots
d. h/o femur fracture
What is c. h/o bood clots
Name 3 foods that are high-purine and should be avoided with gout.
salmon, sardines, organ meats, alcohol, mushrooms, legumes, organ meats, oatmeal.