Pharmacology Terms
a set of laws passed by Congress in 1938 giving authority to the U.S. Food and Drug Administration (FDA) to oversee the safety of food, drugs, medical devices, and cosmetics.
Food, Drug and Cosmetic act
_____soluble drugs are easily absorbed through membranes
Lipid
Stimulation of this receptor increases heart rate
Beta 1 receptor
Injection of a portion of the TB bacterium into the skin to determine previous exposure
PPD purified protein derivative
The maximum number of carpules of anesthetics we should give in patients taking a non-selective beta blocker
2 carpules
A drug who has no accepted medical purpose
Schedule 1 drug
The hepatic system which metabolizes drugs
Cytochrome P450 system
Stimulation results in bronchodilation
Beta 2 receptor
Why is tuberculosis so difficult to treat?
Slow bacterial growth rate
The primary cholinergic receptor of concern in the practice of dentistry
Muscarinic
Tasked with assuring a drug is safe for public use
The food and drug administration
A larger initial dose of a drug to achieve a steady state quickly
Loading dose
Results in a decrease in heart rate and increased blood flow to the stomach and genitals
Parasympathetic stimulation
Taking this drug for TB may turn your urine orange
Rifampin
The direct acting cholinergic agent used in dentistry to increase salivary excretion
Pilocarpine(Salagen)
The distance between the safe and toxic dose of a drug
What is therapeutic index
The effect that pH has on the ability of a drug to be absorbed
Ionization
Causes constriction of blood vessels, often found in cold medications to decrease nasal congestion
Alpha-1 receptor stimulation
Hepatitis is a major side effect of this medication in patients treated for TB exposure OR active illness
Isoniazid
The prototypical non-selective beta blocker used for anxiety, migraine headaches and occasionally blood pressure
Propranolol
A warning label placed on a drug with a well documented and serious side effect of treatment
Black Box Warning
The amount of drug available to interact with receptors
Bioavailability
Found on the presynaptic neuron which prevents the release of norepinephrine, thus decreasing vasoconstriction.
Alpha-2 receptor
Patient being treated with isoniazid for TB prophylaxis should probably avoid which medication or pain?
Tylenol(acetaminophen)
Class of agents which act to keep acetylcholine in the synaptic cleft often used in Alzheimer's disease
Cholinesterase inhibitors