Eyes/Glaucoma
How do mydriatics work?
How do sympathomimetics affect IOP?
They mimic epinephrine and norepinephrine; stimulates dilator muscles to contract, increasing outflow of aqueous humor
Which tricyclic antidepressant is also used for insomnia and neuropathic pain?
Amitriptyline
What are examples of SNRIs?
Duloxetine
What meds are non-selective NSAIDs?
Ibuprofen, Aspirin, Diclofenac, Naproxen, Indomethacin
How to miotics work?
they constrict the pupil
How to beta-adrenergic blockers affect IOP?
They reduce aqueous humor formation and increases outflow
What is the MOA for MAOIs?
blocks monoamine oxidase, which normally breaks down excess tyramine
What are examples of NDRIs?
Bupropian
What meds are selective NSAIDs?
Celebrex
How do cycloplegics work?
They paralyze the ciliary body
What are examples of carbonic anhydrase inhibitors?
Brinzolamide and Dorzolamide
What foods containing tyramine should pts on MAOIs avoid?
Aged cheese, sour cream, yogurt, beef/chicken liver, pickled ferring, fermented meats, undistilled alcohol, caffeine, chocolate, yeast extract & soy sauce
What herb should patients on SSRIs avoid?
St. John's Wort
Which is the max dose for the non-NSAID acetaminophen?
2000-3000 mg/day
What condition inhibits the normal flow and drainage of aqueous humor in the eye?
Glaucoma
What are examples of osmotic diuretics used to decrease IOP?
Glycerin, Mannitol, Isosorbide
What are examples for SSRIs?
Citalopram and Fluoxetine
How long does it take for an antidepressant to fully take effect?
About 6 weeks
What are contraindications for Acetaminophen?
Liver Issues and Alcohol consumption
How do cholinergic drugs affect the eye?
They cause pupillary constriction, which leads to reduced IOP
What are examples of prostaglandin agonists used for glaucoma?
Latanoprost, Travoprost, Bimatoprost, Tafluprost
What are s/s of serotonin syndrome?
Delirium, agitation, tachycardia, sweating, muscle spasms, hyperreflexia, tremors
What are the benefits of second-gen antidepressants such as vortioxetine?
fever adverse effects; can cause insomnia, weight gain and sexual dysfunction
What is the antidote for acetaminophen?
Acetylcystein Regimen