Mechanism of Action
Indications and Clinical Use
Side Effects and Safety
Black Box Warnings
Drug-Drug Interactions
100

This SSRI selectively inhibits the reuptake of serotonin in the synaptic cleft.

What is Fluoxetine (Prozac)?

100

This medication is FDA-approved for bipolar depression and seizure control.

What is Lamotrigine (Lamictal)?

100

Which SSRI is associated with the highest risk of discontinuation syndrome?

What is Paroxetine (Paxil)?

100

All antidepressants carry a black box warning for this serious adverse effect in young adults and adolescents.

What is suicidal ideation?

100

SSRIs inhibit which cytochrome P450 enzyme, potentially increasing the levels of drugs like warfarin and tricyclic antidepressants?

What is CYP2D6?

200

This mood stabilizer inhibits inositol monophosphatase and modulates sodium transport across membranes.

What is Lithium?

200

Which antipsychotic is considered the gold standard for treatment-resistant schizophrenia?

What is Clozapine (Clozaril)?

200

This antipsychotic has a high metabolic side effect profile, including weight gain and diabetes risk.

What is Olanzapine (Zyprexa)?

200

Clozapine carries a black box warning for which life-threatening condition?

What is agranulocytosis?

200

Concurrent use of MAOIs and SSRIs can result in this life-threatening condition.

What is serotonin syndrome?

300

Which antipsychotic works as a partial dopamine agonist at D2 receptors and a serotonin agonist at 5-HT1A receptors?

What is Aripiprazole (Abilify)?

300

Name the SNRI indicated for both depression and neuropathic pain management.

What is Duloxetine (Cymbalta)?

300

Which medication has a black box warning for Stevens-Johnson Syndrome and requires slow titration?

What is Lamotrigine (Lamictal)?

300

Which medication class carries a black box warning for increased mortality in elderly patients with dementia-related psychosis?

What are antipsychotics?

300

Which antipsychotic should be avoided with QT-prolonging medications due to the risk of torsades de pointes?

What is Ziprasidone (Geodon)?

400

Which neurotransmitter is primarily targeted by benzodiazepines to produce their anxiolytic effect?

What is GABA?

400

Which long-acting injectable (LAI) antipsychotic requires oral overlap for the first 3 weeks?

What is Risperdal Consta?

400

What is the most common side effect of lithium therapy?

What is tremor?

400

Which benzodiazepine carries a black box warning for concurrent use with opioids due to the risk of respiratory depression?

What is Lorazepam (Ativan)?

400

Carbamazepine induces which cytochrome enzyme, leading to reduced efficacy of oral contraceptives?

What is CYP3A4?

500

Name the antipsychotic that blocks both dopamine D2 and serotonin 5-HT2A receptors to reduce positive and negative symptoms of schizophrenia.

What is Risperidone (Risperdal)?

500

Which stimulant is commonly used for ADHD but requires a high-fat meal for optimal absorption?

What is Vyvanse (Lisdexamfetamine)?

500

Which SNRI is known for causing dose-dependent increases in blood pressure? 

What is Venlafaxine (Effexor)?

500

Valproic acid has a black box warning for hepatotoxicity, pancreatitis, and which other condition?

What is fetal neural tube defects?

500

Which mood stabilizer's levels can be affected by changes in sodium intake and dehydration?

What is Lithium?

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