Terminology
A base, sugar, and phosphate are called?
Nucleotide
Dominent alleles are represented by capital letters or lower case letters in Punnett squares?
Capital letter (ex. BB)
Used to detect changes in genes or chromosomes of fetus before birth
Prenatal Diagnostic Testing
The characteristics and qualities that are genetically passed from one generation to the next through reproduction
Hereditary
Gene therapy does not have limited therapy. True or False?
False
example: Viruses used for gene transfer can induce viral disease and can be immunogenic in the human host.
A nucleic acid that carries genetic information in the cell
DNA
What does DNA stand for?
Deoxyribonucleic acid (DNA)
Testing used to establish biologic relationships between people
Parental testing
Any disease that develops in response to external factors and is not directly related to a persons genetic makeup
Acquired disease
What is used to manufacture a recombinant form of human insulin
Escherichia coli bacteria
To receive a trait from an ancestor
Inherit
What was the goal of the Human Genome Project (HGP)?
To mapped out and identify the estimated 30,000 genes and 3 billion base pairs in the DNA of an entire human genome
Screening used to identify unaffected individuals who carry one copy of a gene
Carrier screening
A disease caused by passage of a genetic defect from parents to offspring
Inherited disease
rDNA technology can make what recombinant forms of biological drugs?
Biologic drugs such as hormones, vaccines, antitoxins and monoclonal antibodies use rDNA technology.
The observed characteristic of an organism
Phenotype
How do the 4 DNA bases pair up on a sequence? Hint: Adenine (A), Guanine (G), Thymine (T), and Cytosine (C)
1) Adenine (A) with Thymine (T)
2) Guanine (G) with Cytosine (C)
Testing used to diagnose, rule out or confirm a specific genetic or chromosomal condition
Diagnostic testing
The study of the structure, function, and inheritance of genes
Genetics
Genetic tests can be obtained by what method?
A persons blood, skin, hair or saliva can be used for genetic testing. Tissues and cells can also be obtained prenatally.
A diagram tool used to predict trait inheritance
Punnett Square
Humans normally have how many pairs of chromosomes?
23 pairs of chromosomes
Most widespread use of genetic testing. What screening is used for early interventions to treat these disorders and can eliminate or reduce symptoms that may otherwise cause a lifetime of disability
Newborn screening
The study of the structure and function of the genome, and the way genes and their products work in both health and disease.
Genomics
What can be used in gene transfer? Hint: Vector
Viruses