NSAIDS
MS Drugs
Parkinson's Drugs
Sedative-Hypnotics
Local Anesthetics
100
Link the type of inhibition: Ibuprofen, Acetominophen, Aspirin Irreversible, Minor, Competitive
What are: Apirin- Irreversible, Ibuprofen- Competitive, Acetominophen- Minor?
100
This MS drug's side effects include injection site reactions, flu-like symptoms, depression, hepatotoxicity, pregnancy risk, and allergy.
What is Interferon Beta?
100
TRAP! Lose 100 points unless you can describe the classical clinical picture of Parkinson's disease.
What is "Tremor, Rigidity, Akinesia, and Postural instability"?
100
The mechanism of action of the BZPs.
What is, increase the freq of firing of GABA Cl channels?
100
DAILY DOUBLE!!! The reason why esters cause allergic reactions? The reason why amides cause allergic reactions?
What is, metabolism to para-aminobenzoic acid? What is, they put additives in that cause allergies?
200
The third member of this clinical triad: Aspirin sensitivity, Nasal polyps, and ....
What is Asthma?
200
These two future MS drugs are highly anticipated because of its high efficacy and oral dosing.
What are fingolimod and cladribine?
200
These two classes of Parkinson's drugs inhibit the breakdown of Dopamine. Name the classes and also the clinical effect
What are MAOI inhibitors, COMT inhibitors, and they increase "on" time?
200
This BZP is the only one commonly used for outpatient control of seizures.
What is Clonazepam?
200
Name two of the three most important local anesthetic toxicities.
What is 1. CNS toxicity, 2. Cardiovascular toxicity, 3. Peripheral nerve toxicity
300
This disorder somehow related to NSAIDS is characterized by tinnitus, respiratory alkalosis, and metabolic acidosis.
What is acute salicylism?
300
Dalfampridine blocks axonal K channels, this is paradoxically used for
What are MS and palliative therapy to improve walking?
300
One of our lecturers would rather drive with a treated schizophrenic than a person with Parkinsons treated with:
What are ropinirole, pramipexole?
300
This drug is metabolized in the krebs cycle to water and CO2.
What is Sodium Oxybate?
300
This class of local anesthetics can cause methemoglobinemia.
What are Amides, esp. Prilocaine?
400
This drug protects against GI irritation from NSAIDs.
What is misoprostol? Double negative points for saying H2 Blocker.
400
This drug has severe cardiotoxic effects.
What is mitroxantrone?
400
The reason Impulse Control Disorders tend to be associated with dopamine agonists in PD
What is the D3 receptor? Also, probably serotonin?
400
Dexmedetomidine is becoming popular because it combines anxiolysis, sedation, AND analgesia. These are an adverse effects.
What are hypotension and bradycardia?
400
This is why amide local anesthetics can cause allergic reactions.
What are additives?
500
This NSAID is used to close neonatal patent ductus arteriousus.
What is indomethacin?
500
An MS med was taken off the market (and later returned) because it caused what disease?
What is progressive multifocal leukencephalopathy?
500
The reason why food interferes with the absorption of this Parkinson's medication.
What is Levodopa, and because it is transported via amino acid transporters?
500
This class of sedative hypnotics can induce porphyrin synthesis- very rarely clinically relevant.
What are Barbituates?
500
Explain Fetal toxicity, Carbonation, and ion trapping.
What is acid/base behavior of local anesthetics?
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