Schedule I No medical use, high abuse potential - Heroin
Schedule II Acceptable medical use, High abuse potential - Amphetamine
Schedule III Acceptable medical use, Moderate abuse potential - Limited amounts of opium/Morphine
Schedule IV Acceptable medical use, low abuse potential - Diazepam
Schedule V Acceptable medical use, Abuse potential - Cough supressants
Salvation, Lacrimation, Urination, Defecation, Gastritis, Emesis
Parasympathomimetic
Pharmacodynamics is the study of a drugs actions, or effects, on the body.
Pharmacokinetics is the study of the absorbtions, distribution, biotransformation (metabolism) and elimination of a drug.
Channels and pores, Transport System, Direct Penetration
Direct penetration ;)
Alpha1 is mostly vasoconstriction with mild bronchoconstriction, and increased metabolism. Located in the post-synaptic junction
Alpha2 serve as inhibitors of excess norepinephrine release (prevents over constriction) Located in the pre synaptic junction
Beta1 Increased heart rate (positive chronotropy), Increased contractile force (positive inotropy), Increased conduction (Positive Dromotropy), Release of renin from the kidneys. Located in the cardiac muscles
Beta2 Dilation of arterioles, Dilation of bronchi, Inhibition of uterine contraction, Tremors in Skeletal muscle. Located in smooth muscle
Class I Sodium channel blockers - 1A Procainamide, 1B Lidocaine
Class II Beta-Blockers - Non-selective Beta Blocker Propranolol, Beta1 selective Esmolol and acebutolol
Class III Potassium Channel Blockers - Bretylium
Class IV Calcium Channel Blockers - Diltiazem
Class Miscellaneous - Adenosine and Mag Sulfate
Enteric absorptions - Involves the gastrointestinal tract
Parenteric absorption - Avoids portal circulation goes around the gastrointestinal tract
Diuretics, Sympathetic inhibiting Agents (beta blockers and antidrenergics). ACE inhibitors, Clacium Channel blocker, Direct vasoconstriction