ACEI's & CCB's
MOA's
Adverse Effects
Location of Action
Grab Bag
100
Amlodipine, Nicardipine, and Nifedipine belong to this class of calcium channel blockers.
What is Dihydropyridines?
100
Inhibits the Na/K/2Cl co-transport system in the thick ascending limb of the Loop of Henle.
What is Furosemide?
100
Gout, hypokalemia, and auditory disturbances.
What is Furosemide?
100
Thick ascending loop of henle.
What are Loop diuretics?
100
This group of anti-hypertensives tends to cause 'taste changes' as a side-effect.
What are ACEI's?
200
ACEI's may cause damage to this organ in a developing fetus.
What are the kidneys?
200
This class of anti-hypertensive is a competitive aldosterone receptor antagonist in the cortical collecting tubule.
What is Potassium-sparing diuretics?
200
Lupus-like syndrome.
What is Hydralazine?
200
Proximal convoluted tubule only.
What is Acetazolamide?
200
Coughing associated with ACEI's warrants switching to this type of drug.
What are ARB's (Angiotensin-receptor blockers)?
300
This chemical is responsible for the cough associated with Captopril use.
What is Bradykinin?
300
This class of drug is a potent vasodilator that reduces the levels of angiotensin 2 and prevents the inactivation of bradykinin.
What are ACE inhibitors?
300
Metabolic alkalosis and wasting of potassium.
What are Loop diuretics?
300
PCT.
What are Thiazides?
300
This drug is used when massive diuresis is required.
What is Furosemide?
400
This calcium channel blocker has the strongest impact on vascular smooth muscle.
What is Nifedipine?
400
Reduces total body HC03- stores by acting in the proximal convoluted tubule.
What is Acetazolamide?
400
Constipation, peripheral edema, and flushing.
What are Calcium channel blockers?
400
Collecting ducts only.
What are ADH antagonists?
400
Addition of this type of drug will help to prevent reflex tachycardia when using Hydralazine.
What is a beta-blocker?
500
This calcium channel blocker is least likely to cause an arrhythmia.
What is Nifedipine?
500
An osmotic diuretic that increases tubular fluid osmolarity.
What is Mannitol?
500
Causes 'Monday disease'.
What is Nitroglycerine?
500
PCT, thin descending limb of Henle, and collecting ducts.
What is Mannitol?
500
Hydralazine works by increasing this second-messenger.
What is cyclic GMP (cGMP)?
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