Rx
The science dealing with actions of drugs in the body.
What is Pharmacology?
This is the first stage in the process.
What is absorption?
This is the second stage of this process in which medication is dispersed throughout the body via bloodstream.
What is Distribution?
This is an inactive form of medication after enzymatic breakdown in the liver.
What are metabolites?
This is the final stage of Pharmacokinetics in which drugs are removed by the body.
What is Excretion?
Medications or other substances that have a physiologic effect in the body.
What are drugs?
This process occurs when a client takes drugs orally, enterally, or rectally.
What is First Pass Effect?
This is an abundant plasma protein in the blood.
What is albumin?
This is the sctive form of medication after enzymztic breakdown in the liver.
This is the most common route of excretion.
What is Kidneys?
The study of how a person's genetic make-up affects their response to medicines.
What is Pharmacogentics?
Medications administered by this route have immediate results.
What is inhalation, nasally, Intramuscularly, subcutaneously, topically, or intraveneously
This is the portion of medication dissolved in plasma water and floats freely until crossing the cell membrane.
What is Free Drug?
The process where orally administered medications are broken down in the liver (and intestines).
What is First-Pass Effect?
This route of excretion occurs with bile.
What is the liver?
The study of how drugs act at target sites of action in the body.
What is Pharmacodynamics?
The percentage of medication that reaches the systemic circulation.
What is bioavailability?
This barrier protects the brain from potentially dangerous substances, such as poisons or viruses.
What is the Blood-Brain Barrier?
This is the amount of time it takes for half of the medication to be elimated in the body.
What is Half-Life?
These are specific labs to monitor for kidney function.
What are Creatinine, Glomular Filtration Rate (GFR), and Creatinine Clearance?
The study of how the body absorbs, distributes, metabolizes, and eliminates drugs.
What is Pharmacokinetics?
Absorption of medication by this route is slower and affected by blood flow circulation to the skin.
What is Transdermal route?
These are factors that may alter how a medication is distributed in the body.
What is blood flow, plasma protein binding, lipid solubility, blood-brain barrier, & placental barrier?
This substance affects the metabolizing rates of some medications.
What is grapefruit juice (CYP3A4)?
These are specific labs to monitor for liver function.
What are Liver Function Tests (LFT), ALT and AST?
The process shows how a medication functions in the body.
What Mechanism of Action?
A drug type that binds tightly to a receptor to produce a desired effect.
What is an Agonist?
A drug type that competes with other molecules to block a specific action or response at the receptor site.
What is an Antagonist?
As the dose of a medication increases, the response should increase.
What is Dose-Response?
These 3 principles relate to the effects of a medication on a client.
What is Onset, Peak, and Duration?